Product Name
Alcohol dehydrogenase class-3 (Adh5), Polyclonal Antibody
Full Product Name
Rabbit anti-mouse Alcohol dehydrogenase class-3 polyclonal Antibody, Biotin conjugated
Product Synonym Names
Alcohol dehydrogenase 2; Alcohol dehydrogenase 5; Alcohol dehydrogenase B2; ADH-B2; FALDH; FDH; GSH-FDH; Adh5; Adh-2; Adh2
Product Gene Name
anti-Adh5 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P28474
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-Adh5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Adh5 antibody
Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.
Applications Tested/Suitable for anti-Adh5 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for Adh5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001275507.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001288578.1
[Other Products]
UniProt Primary Accession #
P28474
[Other Products]
UniProt Secondary Accession #
Q3TW83; Q8C662[Other Products]
UniProt Related Accession #
P28474[Other Products]
Molecular Weight
39,548 Da[Similar Products]
NCBI Official Full Name
alcohol dehydrogenase class-3 isoform 2
NCBI Official Synonym Full Names
alcohol dehydrogenase 5 (class III), chi polypeptide
NCBI Official Symbol
Adh5 [Similar Products]
NCBI Official Synonym Symbols
Adh3; Adh-5; GSNOR
[Similar Products]
NCBI Protein Information
alcohol dehydrogenase class-3
UniProt Protein Name
Alcohol dehydrogenase class-3
UniProt Synonym Protein Names
Alcohol dehydrogenase 2; Alcohol dehydrogenase 5; Alcohol dehydrogenase B2; ADH-B2; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase (EC:1.1.1.-); FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase (EC:1.1.1.284)
Protein Family
Alcohol dehydrogenase
UniProt Gene Name
Adh5 [Similar Products]
UniProt Synonym Gene Names
Adh-2; Adh2; ADH-B2; FALDH; FDH; GSH-FDH [Similar Products]
UniProt Entry Name
ADHX_MOUSE
UniProt Comments for Adh5
ADH5: Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Protein type: Lipid Metabolism - fatty acid; EC 1.1.1.1; Oxidoreductase; Mitochondrial; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Energy Metabolism - methane; Cofactor and Vitamin Metabolism - retinol; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.1.1.284; Amino Acid Metabolism - tyrosine
Cellular Component: cytoplasm; mitochondrion; nucleus
Molecular Function: (R)-2-hydroxyglutarate dehydrogenase activity; (R)-2-hydroxyisocaproate dehydrogenase activity; 2-hydroxytetrahydrofuran dehydrogenase activity; 3-ketoglucose-reductase activity; 5-exo-hydroxycamphor dehydrogenase activity; acetoin dehydrogenase activity; alcohol dehydrogenase activity; aldo-keto reductase activity; arabinose reductase activity; C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity; D-arabinitol dehydrogenase (NADP+) activity; epoxide dehydrogenase activity; fatty acid binding; formaldehyde dehydrogenase activity; gluconate dehydrogenase activity; isocitrate dehydrogenase activity; metal ion binding; mevaldate reductase activity; oxidoreductase activity; phenylcoumaran benzylic ether reductase activity; protein homodimerization activity; S-(hydroxymethyl)glutathione dehydrogenase activity; steroid dehydrogenase activity; steroid dehydrogenase activity, acting on the CH-CH group of donors; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; xylose reductase activity; zinc ion binding
Biological Process: ethanol catabolic process; ethanol oxidation; formaldehyde catabolic process; peptidyl-cysteine S-nitrosylation; positive regulation of blood pressure; respiratory system process; response to lipopolysaccharide; response to nitrosative stress; response to redox state; retinoid metabolic process
Research Articles on Adh5
1. Results show that ADH5 removes endogenous formaldehyde to prevent DNA adducts, and protects with FANCD2, hematopoietic stem cells, hepatocytes, and nephrons from endogenous DNA damage.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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