Full Product Name
GHR Polyclonal Antibody
Product Synonym Names
GHR; GHBP; Growth hormone-binding protein; Serum-binding protein
Product Gene Name
anti-GHR antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P10912
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Immunogen
A synthetic peptide of human GHR
Calculated Molecular Weight
69kDa
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Notes
Small volumes of anti-GHR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GHR antibody
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.
Product Categories/Family for anti-GHR antibody
Polyclonal
Applications Tested/Suitable for anti-GHR antibody
Western Blot (WB)
Application Notes for anti-GHR antibody
WB: 1:500 - 1:2000
Western Blot (WB) of anti-GHR antibody
Western blot analysis of extracts of PC cells, using GHR antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
NCBI/Uniprot data below describe general gene information for GHR. It may not necessarily be applicable to this product.
NCBI Accession #
P10912.1
[Other Products]
UniProt Primary Accession #
P10912
[Other Products]
UniProt Secondary Accession #
Q9HCX2[Other Products]
UniProt Related Accession #
P10912[Other Products]
NCBI Official Full Name
Growth hormone receptor
NCBI Official Synonym Full Names
growth hormone receptor
NCBI Official Symbol
GHR [Similar Products]
NCBI Official Synonym Symbols
GHBP
[Similar Products]
NCBI Protein Information
growth hormone receptor; GH receptor; serum binding protein; somatotropin receptor; growth hormone binding protein
UniProt Protein Name
Growth hormone receptor
UniProt Synonym Protein Names
Somatotropin receptorGrowth hormone-binding protein; GH-binding protein; GHBPAlternative name(s):Serum-binding protein
UniProt Gene Name
GHR [Similar Products]
UniProt Synonym Gene Names
GH receptor; GH-binding protein; GHBP [Similar Products]
UniProt Entry Name
GHR_HUMAN
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
