Product Name
SGCB/SGC/Sarcoglycan Beta, Monoclonal Antibody
Full Product Name
Anti-SGCB/SGC/Sarcoglycan Beta Antibody (clone 1E3)
Product Synonym Names
Rabbit Polyclonal to Human SGCB/SGC/Sarcoglycan Beta; SGCB; 43DAG; Beta-sarcoglycan; Beta-SG; A3b; LGMD2E; SGC
Product Gene Name
anti-SGCB antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q16585
Purity/Purification
Purified from ascites by Protein A
Immunogen
SGCB (AAH20709, 1 a.a. ~ 319 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Preparation and Storage
Store at -20 degree C.
Aliquot to avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-SGCB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SGCB antibody
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actincytoskeleton and the extracellular matrix.
Applications Tested/Suitable for anti-SGCB antibody
ELISA (EIA), Immunohistochemistry (IHC) Formalin, Western Blot (WB)
Application Notes for anti-SGCB antibody
IHC-Fr: 1:50
Immunohistochemistry (IHC) of anti-SGCB antibody
IHC with SGCB antibody on frozen human heart.

ELISA (EIA) of anti-SGCB antibody
Detection limit for recombinant GST tagged SGCB is approximately 0.3 ng/ml as a capture antibody.

NCBI/Uniprot data below describe general gene information for SGCB. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000223.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000232.4
[Other Products]
UniProt Primary Accession #
Q16585
[Other Products]
UniProt Secondary Accession #
O00661; B7Z635[Other Products]
UniProt Related Accession #
Q16585[Other Products]
Molecular Weight
26,924 Da
NCBI Official Full Name
beta-sarcoglycan
NCBI Official Synonym Full Names
sarcoglycan beta
NCBI Official Symbol
SGCB [Similar Products]
NCBI Official Synonym Symbols
A3b; SGC; LGMD2E
[Similar Products]
NCBI Protein Information
beta-sarcoglycan
UniProt Protein Name
Beta-sarcoglycan
UniProt Synonym Protein Names
43 kDa dystrophin-associated glycoprotein; 43DAG; A3b
Protein Family
Beta-sarcoglycan
UniProt Gene Name
SGCB [Similar Products]
UniProt Synonym Gene Names
Beta-SG; 43DAG [Similar Products]
NCBI Summary for SGCB
This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.[provided by RefSeq, Oct 2008]
UniProt Comments for SGCB
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Research Articles on SGCB
1. This study demonstrated that LGMD2E is the most common type of sarcoglycanopathies in the Iranian population.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.