Product Name
Proteasome assembly chaperone 4 (PSMG4), Recombinant Protein
Full Product Name
Recombinant Human Proteasome assembly chaperone 4 (PSMG4)
Product Gene Name
PSMG4 recombinant protein
[Similar Products]
Product Synonym Gene Name
PSMG4[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-123aa, full length protein
Sequence
MEGLVVAAGG DVSLHNFSAR LWEQLVHFHV MRLTDSLFLW VGATPHLRNL AVAMCSRYDS IPVSTSLLGD TSDTTSTGLA QRLARKTNKQ VFVSYNLQNT DSNFALLVEN RIKEEMEAFP EKF
3D Structure
ModBase 3D Structure for Q5JS54
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PSMG4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PSMG4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001122063.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001128591.1
[Other Products]
UniProt Primary Accession #
Q5JS54
[Other Products]
UniProt Secondary Accession #
Q5JS53; Q5JS56; C9J2F8; F8WBZ2[Other Products]
UniProt Related Accession #
Q5JS54[Other Products]
Molecular Weight
11,216 Da
NCBI Official Full Name
proteasome assembly chaperone 4 isoform b
NCBI Official Synonym Full Names
proteasome assembly chaperone 4
NCBI Official Symbol
PSMG4 [Similar Products]
NCBI Official Synonym Symbols
PAC4; C6orf86; bA506K6.2
[Similar Products]
NCBI Protein Information
proteasome assembly chaperone 4
UniProt Protein Name
Proteasome assembly chaperone 4
Protein Family
Proteasome assembly chaperone
UniProt Gene Name
PSMG4 [Similar Products]
UniProt Synonym Gene Names
C6orf86; PAC4; PAC-4; hPAC4 [Similar Products]
UniProt Comments for PSMG4
Chaperone protein which promotes assembly of the 20S proteasome.
Research Articles on PSMG4
1. PSMG4 and NLRP5 appear of particular interest as they were found to be associated with more than one clinical phenotype and are implicated in
biological processes considered relevant to the pathophysiology of MS. Also, PSMG4 p.W99R and NLRP5 p.R761L were found to correlate with an earlier age of MS clinical onset. Our data suggests PSMG4 and NLPR5 as potential targets for the development of modifying therapies for MS.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.