Product Name
ADP-ribosylation factor-like protein 13B (arl13b), Recombinant Protein
Full Product Name
Recombinant Danio rerio ADP-ribosylation factor-like protein 13B (arl13b)
Product Gene Name
arl13b recombinant protein
[Similar Products]
Product Synonym Gene Name
arl13b[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-407aa, full length protein
Sequence
MFNLMANCCN WLKRWREPAR KVTLVMVGLD NAGKTATVRG IQGESPLDVA PTVGFSKVDL KQGKFEVTIF DLGGGKRIRG IWKNYYSESY GVVFVVDSSD VQRIQETRDT MAEVLRHPRI AGKPVLVLAN KQDQDGAMAE ADIIETLSLE KLVNENKCLC QIEPCSAVLG YGKKVDKSIK NGLNWLLNNI AKDYEAISER VQKDTAEQKA QEEQDKKERA ERVRRIREER DRQEREEAER EGRTLKEEEL DDVNMFNPFQ PINNVLTENQ DRLNREKEMQ RQRENGQQGS VQEQIALQDE EEEEEDEESE RQTPESTESG AVDQTKKKTR KLRLKRKHRV DPLRMEEAAP KSPTPPPLPV GWATPKVSRL PKLEPLGDTR HSDFYGKPLP PVAIRQRPNS DTHDVIS
3D Structure
ModBase 3D Structure for Q8JHI3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of arl13b recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for arl13b. It may not necessarily be applicable to this product.
NCBI Accession #
NP_775379.1
[Other Products]
NCBI GenBank Nucleotide #
NM_173272.1
[Other Products]
UniProt Primary Accession #
Q8JHI3
[Other Products]
UniProt Secondary Accession #
Q561Z5[Other Products]
UniProt Related Accession #
Q8JHI3[Other Products]
Molecular Weight
46,566 Da
NCBI Official Full Name
ADP-ribosylation factor-like protein 13B
NCBI Official Synonym Full Names
ADP-ribosylation factor-like 13b
NCBI Official Symbol
arl13b [Similar Products]
NCBI Official Synonym Symbols
arl2l1; fc23g07; chunp6872; wu:fc23g07; zgc:123149
[Similar Products]
NCBI Protein Information
ADP-ribosylation factor-like protein 13B
UniProt Protein Name
ADP-ribosylation factor-like protein 13B
UniProt Synonym Protein Names
ADP-ribosylation factor-like protein 2-like 1; ARL2-like protein 1; Protein scorpion
UniProt Gene Name
arl13b [Similar Products]
UniProt Synonym Gene Names
arl2l1; ARL2-like protein 1 [Similar Products]
UniProt Comments for arl13b
Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex Required during embryogenesis for cilia formation in multiple organs such as the pronephric duct.
Research Articles on arl13b
1. loss of Arl13b leads to slow photoreceptor degeneration, but can be exacerbated by the loss of vangl2. Importantly, the data show that Arl13b can genetically and physically interact with Vangl2 and this association is important for normal photoreceptor structure.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
