Product Name
Thiamine transporter 1 (SLC19A2), Recombinant Protein
Full Product Name
Recombinant Human Thiamine transporter 1 (SLC19A2), partial
Product Gene Name
SLC19A2 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MDVPGPVSRR AAAAAATVLL RTARVRRECW FLPTALLCAY GFFASLRPSE PFLTPYLLGP DKNLTEREVF NEIYPVWTYS YLVLLFPVFL ATDYLRYKPV VLLQGLSLIV TWFMLLYAQG LLAIQFLEFF YGIATATEIA YYSYIYSVVD LGMYQKVTSY CRSATLVGFT VGSVLGQILV SVAGWSLFSL NVISLTCVSV AFAVAWFLPM PQKSLFFHHI PSTCQRVNGI KVQNGGIVTD TPASNHLPGW EDIESKIPLN MEEPPVEEPE PKPDRLLVLK VLWNDFLMCY SSRPLLCWSV WWALSTCGYF QVVNYTQGLW EKVMPSRYAA IYNGGVEAVS TLLGAVAVFA VGYIKISWST WGEMTLSLFS LLIAAAVYIM DTVGNIWVCY ASYVVFRIIY MLLITIATFQ IAANLSMERY ALVFGVNTFI ALALQTLLTL IVVDASGLGL EITTQFLIYA SYFALIAVVF LASGAVSVMK KCRKLEDPQS SSQVTTS
3D Structure
ModBase 3D Structure for O60779
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SLC19A2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SLC19A2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001306596.1
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NCBI GenBank Nucleotide #
NM_001319667.1
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UniProt Primary Accession #
O60779
[Other Products]
UniProt Secondary Accession #
Q8WV87; Q9UBL7; Q9UKJ2; Q9UN31; Q9UN43; B2R9H0; B4E1X4[Other Products]
UniProt Related Accession #
O60779[Other Products]
Molecular Weight
32,858 Da
NCBI Official Full Name
thiamine transporter 1 isoform 2
NCBI Official Synonym Full Names
solute carrier family 19 member 2
NCBI Official Symbol
SLC19A2 [Similar Products]
NCBI Official Synonym Symbols
TC1; THT1; TRMA; THMD1; THTR1
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NCBI Protein Information
thiamine transporter 1
UniProt Protein Name
Thiamine transporter 1
UniProt Synonym Protein Names
Solute carrier family 19 member 2; Thiamine carrier 1; TC1
Protein Family
Thiamine transporter
UniProt Gene Name
SLC19A2 [Similar Products]
UniProt Synonym Gene Names
THT1; TRMA; ThTr-1; ThTr1; TC1 [Similar Products]
NCBI Summary for SLC19A2
This gene encodes the thiamin transporter protein. Mutations in this gene cause thiamin-responsive megaloblastic anemia syndrome (TRMA), which is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
UniProt Comments for SLC19A2
High-affinity transporter for the intake of thiamine.
Research Articles on SLC19A2
1. T], p.[(Val69Phe)] causing thiamine responsive megaloblastic anemia syndrome.">A novel homozygous SLC19A2 gene mutation c.[205G>T], p.[(Val69Phe)] causing thiamine responsive megaloblastic anemia syndrome.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
