Full Product Name
HOXB8 Antibody
Product Gene Name
anti-HOXB8 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P17481
Species Reactivity
Human, Mouse, Rat
Concentration
1.0mg/ml (lot specific)
Other Notes
Small volumes of anti-HOXB8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-HOXB8 antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for HOXB8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_076921.1
[Other Products]
NCBI GenBank Nucleotide #
NM_024016.3
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UniProt Primary Accession #
P17481
[Other Products]
UniProt Secondary Accession #
Q9H1I2[Other Products]
UniProt Related Accession #
P17481[Other Products]
Molecular Weight
27,574 Da
NCBI Official Full Name
homeobox protein Hox-B8
NCBI Official Synonym Full Names
homeobox B8
NCBI Official Symbol
HOXB8 [Similar Products]
NCBI Official Synonym Symbols
HOX2; HOX2D; Hox-2.4
[Similar Products]
NCBI Protein Information
homeobox protein Hox-B8
UniProt Protein Name
Homeobox protein Hox-B8
UniProt Synonym Protein Names
Homeobox protein Hox-2.4; Homeobox protein Hox-2D
Protein Family
Homeobox protein
UniProt Gene Name
HOXB8 [Similar Products]
UniProt Synonym Gene Names
HOX2D [Similar Products]
NCBI Summary for HOXB8
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq, Jul 2008]
UniProt Comments for HOXB8
HOXB8: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 17q21.32
Biological Process: negative regulation of myeloid cell differentiation
Research Articles on HOXB8
1. Results show that FMRP regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 MID domain.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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