Product Name
TECPR2, Polyclonal Antibody
Full Product Name
TECPR2 Antibody, FITC conjugated
Product Synonym Names
Tectonin beta-propeller repeat-containing protein 2; WD repeat-containing protein KIAA0329/KIAA0297; TECPR2; KIAA0297; KIAA0329
Product Gene Name
anti-TECPR2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O15040
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Tectonin beta-propeller repeat-containing protein 2 protein (516-783AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-TECPR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TECPR2 antibody
Probably plays a role as positive regulator of autophagy.
Applications Tested/Suitable for anti-TECPR2 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for TECPR2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001166102.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001172631.2
[Other Products]
UniProt Primary Accession #
O15040
[Other Products]
UniProt Secondary Accession #
Q9UEG6; A5PKY3; A6NFY9; A7E2X3; H0YMM9[Other Products]
UniProt Related Accession #
O15040[Other Products]
Molecular Weight
137,944 Da
NCBI Official Full Name
tectonin beta-propeller repeat-containing protein 2 isoform 2
NCBI Official Synonym Full Names
tectonin beta-propeller repeat containing 2
NCBI Official Symbol
TECPR2 [Similar Products]
NCBI Official Synonym Symbols
SPG49; KIAA0329
[Similar Products]
NCBI Protein Information
tectonin beta-propeller repeat-containing protein 2
UniProt Protein Name
Tectonin beta-propeller repeat-containing protein 2
UniProt Synonym Protein Names
WD repeat-containing protein KIAA0329/KIAA0297
Protein Family
Tectonin beta-propeller repeat-containing protein
UniProt Gene Name
TECPR2 [Similar Products]
UniProt Synonym Gene Names
KIAA0297; KIAA0329 [Similar Products]
UniProt Entry Name
TCPR2_HUMAN
NCBI Summary for TECPR2
The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
UniProt Comments for TECPR2
Probably plays a role as positive regulator of autophagy.
Research Articles on TECPR2
1. The discovery of additional TECPR2 utations in non-Bukharian patients implies that this disease might be more common than previously appreciated
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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