Full Product Name
CCL27 Antibody
Product Gene Name
anti-CCL27 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9Y4X3
Concentration
1.0mg/ml (lot specific)
Other Notes
Small volumes of anti-CCL27 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CCL27 antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for CCL27. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006655.1
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NCBI GenBank Nucleotide #
NM_006664.3
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UniProt Primary Accession #
Q9Y4X3
[Other Products]
UniProt Related Accession #
Q9Y4X3[Other Products]
Molecular Weight
12,618 Da
NCBI Official Full Name
C-C motif chemokine 27
NCBI Official Synonym Full Names
C-C motif chemokine ligand 27
NCBI Official Symbol
CCL27 [Similar Products]
NCBI Official Synonym Symbols
ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27
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NCBI Protein Information
C-C motif chemokine 27
UniProt Protein Name
C-C motif chemokine 27
UniProt Synonym Protein Names
CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; Skinkine; Small-inducible cytokine A27
Protein Family
C-C motif chemokine
UniProt Gene Name
CCL27 [Similar Products]
UniProt Synonym Gene Names
ILC; SCYA27; CTACK [Similar Products]
NCBI Summary for CCL27
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]
UniProt Comments for CCL27
CCL27: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9p13.3
Cellular Component: extracellular region
Biological Process: cell-cell signaling; chemotaxis
Research Articles on CCL27
1. Our data supports previous reports showing IL-17 and -23 upregulation in association with Multiple sclerosis and potentially identify a previously unknown involvement for CCL27.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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