Product Name
Aconitate hydratase, mitochondrial (Aco2), Recombinant Protein
Full Product Name
Recombinant Rat Aconitate hydratase, mitochondrial (Aco2)
Product Gene Name
Aco2 recombinant protein
[Similar Products]
Product Synonym Gene Name
Aco2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
28-780aa, Full Length of Mature Protein
Sequence
QRAKVAMSHF EPSEYIRYDL LEKNINIVRK RLNRPLTLSE KIVYGHLDDP ANQEIERGKT YLRLRPDRVA MQDATAQMAM LQFISSGLPK VAVPSTIHCD HLIEAQLGGE KDLRRAKDIN QEVYNFLATA GAKYGVGFWR PGSGIIHQII LENYAYPGVL LIGTDSHTPN GGGLGGICIG VGGADAVDVM AGIPWELKCP KVIGVKLTGT LSGWTSPKDV ILKVAGILTV KGGTGAIVEY HGPGVDSISC TGMATICNMG AEIGATTSVF PYNHRMKKYL SKTGRADIAN LAEEFKDHLV PDPGCQYDQV IEINLNELKP HINGPFTPDL AHPVADVGTV AEKEGWPLDI RVGLIGSCTN SSYEDMGRSA AVAKQALAHG LKCKSQFTIT PGSEQIRATI ERDGYAQILR DVGGIVLANA CGPCIGQWDR KDIKKGEKNT IVTSYNRNFT GRNDANPETH AFVTSPEIVT ALAIAGTLKF NPETDFLTGK DGKKFKLEAP DADELPRSDF DPGQDTYQHP PKDSSGQRVD VSPTSQRLQL LEPFDKWDGK DLEDLQILIK VKGKCTTDHI SAAGPWLKFR GHLDNISNNL LIGAINIENG KANSVRNAVT QEFGPVPDTA RYYKKHGIRW VVIGDENYGE GSSREHAALE PRHLGGRAII TKSFARIHET NLKKQGLLPL TFADPSDYNK IHPVDKLTIQ GLKDFAPGKP LNCIIKHPNG TQETILLNHT FNETQIEWFR AGSALNRMKE LQQ
3D Structure
ModBase 3D Structure for Q9ER34
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Aco2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Aco2 recombinant protein
This protein belongs to the aconitase
IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
NCBI/Uniprot data below describe general gene information for Aco2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_077374.2
[Other Products]
NCBI GenBank Nucleotide #
NM_024398.2
[Other Products]
UniProt Primary Accession #
Q9ER34
[Other Products]
UniProt Secondary Accession #
Q6P6V3[Other Products]
UniProt Related Accession #
Q9ER34[Other Products]
Molecular Weight
85,433 Da
NCBI Official Full Name
aconitate hydratase, mitochondrial
NCBI Official Synonym Full Names
aconitase 2
NCBI Official Symbol
Aco2 [Similar Products]
NCBI Protein Information
aconitate hydratase, mitochondrial
UniProt Protein Name
Aconitate hydratase, mitochondrial
UniProt Synonym Protein Names
Citrate hydro-lyase
Protein Family
Aconitate hydratase
UniProt Gene Name
Aco2 [Similar Products]
UniProt Synonym Gene Names
Aconitase [Similar Products]
UniProt Comments for Aco2
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
Research Articles on Aco2
1. Ogg1 chaperoning of Aco-2 in preventing oxidant-mediated mtDNA damage and apoptosis may afford an innovative target for the molecular events underlying oxidant-induced toxicity.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
