Product Name
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1), Recombinant Protein
Full Product Name
Recombinant Mesocricetus auratus 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1)
Product Gene Name
HSD3B1 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-373aa; full length protein
Sequence
PGWSCLVTGA GGFLGQRIIR MLVQEKELQE VRALDKVFRP ETREEFCKLQ TKTKVTVLEG DILDAQCLRR ACQGISVVIH TAAAIDVFGA IPRQTIIDIN LKGTLNLLEA CVQASVPAFI YTSSIDVAGP NSYKEIVLNG HEEQQHESTW SDPYPYSKKM AEKAVLAANG SSLKNGGTLH TCALRPMYIY GEKSPLISVT IIRAVKNSGI LDVTGKFSTV NPVYVNNAAW AHILAARGLQ DPRKSPNIQG QFYYISDDTP HQSYDDLNYV LSKDWGLRPD SSWRPPVALL YWLGFLLELV SFLLRPVYNY QPPFNRHLVT LSNTVFTFSY KKAQRDLGYE PLVGWEEARE NTSEWIGSLV EQHKGTLNTK AQ
3D Structure
ModBase 3D Structure for Q60555
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Species
Mesocricetus auratus (Golden hamster)
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of HSD3B1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for HSD3B1 recombinant protein
Transmembrane Protein
Application Notes for HSD3B1 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for HSD3B1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001297496.1
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NCBI GenBank Nucleotide #
NM_001310567.1
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UniProt Primary Accession #
Q60555
[Other Products]
UniProt Secondary Accession #
Q60556[Other Products]
UniProt Related Accession #
Q60555[Other Products]
Molecular Weight
41,754 Da
NCBI Official Full Name
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
NCBI Official Symbol
Hao2 [Similar Products]
NCBI Official Synonym Symbols
HSD3B1
[Similar Products]
NCBI Protein Information
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
UniProt Protein Name
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
UniProt Synonym Protein Names
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I
Protein Family
4-isomerase" title="3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase">3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
UniProt Gene Name
HSD3B1 [Similar Products]
UniProt Synonym Gene Names
3-beta-HSD I [Similar Products]
UniProt Entry Name
3BHS1_MESAU
UniProt Comments for HSD3B1
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes hormonal steroids. Also able to act as 3-keto-reductase reducing 5-alpha-dihydrotestosterone to the corresponding 3-beta-androstan-3-beta,17-beta-diol.
Precautions
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Disclaimer
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