Product Name
40S ribosomal protein S18 (RS18), Recombinant Protein
Full Product Name
Recombinant Human 40S ribosomal protein S18
Product Synonym Names
Ke-3; Ke3
Product Gene Name
RS18 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
Full Length, 2-152aa
3D Structure
ModBase 3D Structure for P62269
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Other Notes
Small volumes of RS18 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
RS18 recombinant protein
Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
NCBI/Uniprot data below describe general gene information for RS18. It may not necessarily be applicable to this product.
NCBI Accession #
NP_072045.1
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NCBI GenBank Nucleotide #
NM_022551.2
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UniProt Primary Accession #
P62269
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UniProt Secondary Accession #
P25232; Q5SUJ3; Q6IPF8[Other Products]
UniProt Related Accession #
P62269[Other Products]
NCBI Official Full Name
40S ribosomal protein S18
NCBI Official Synonym Full Names
ribosomal protein S18
NCBI Official Symbol
RPS18 [Similar Products]
NCBI Official Synonym Symbols
KE3; S18; HKE3; KE-3; D6S218E
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NCBI Protein Information
40S ribosomal protein S18
UniProt Protein Name
40S ribosomal protein S18
UniProt Synonym Protein Names
Ke-3; Ke3; Small ribosomal subunit protein uS13
Protein Family
40S ribosomal protein
UniProt Gene Name
RPS18 [Similar Products]
UniProt Synonym Gene Names
D6S218E; Ke3 [Similar Products]
NCBI Summary for RS18
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Comments for RS18
RPS18: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA. Belongs to the ribosomal protein S13P family.
Protein type: Ribosomal; Translation
Chromosomal Location of Human Ortholog: 6p21.32
Cellular Component: cytosol; extracellular matrix; focal adhesion; membrane; nucleoplasm; nucleus; small ribosomal subunit
Molecular Function: protein binding; RNA binding; structural constituent of ribosome
Biological Process: mRNA catabolic process, nonsense-mediated decay; ribosome biogenesis and assembly; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription
Research Articles on RS18
1. Ribosomal protein S18e seems to act as a molecular staple fixing the 18S rRNA 3'-major domain core.
Precautions
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Disclaimer
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