Full Product Name
Anti-CD32C Antibody (C-Terminus)
Product Synonym Names
Rabbit Polyclonal to Human CD32C; FCGR2C; CD32; CD32 antigen; CDw32; Fc gamma receptor IIC; FCG2; Fc-gamma-RIIc; FcRII-c; FCRIIC; Igg fc receptor ii-c; Fc-gamma rii-c; HFcRII-C; CD32C; IGFR2
Product Gene Name
anti-CD32C antibody
[Similar Products]
Product Synonym Gene Name
FCGR2C[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P31995
Species Reactivity
Human
Predicted: Mouse, Rat
Specificity
Recognizes endogenous levels of CD32c protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.3, 0.01% sodium azide, 30% glycerol.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-terminal region of human CD32c.
Preparation and Storage
Store at -20 degree C.
Aliquot to avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-CD32C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD32C antibody
Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation ofantibody production by B-cells.
Applications Tested/Suitable for anti-CD32C antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-CD32C antibody
IHC-P: 1:100
WB: 1:500-1:1000
Immunohistochemistry (IHC) of anti-CD32C antibody
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry (WB) of anti-CD32C antibody
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western Blot (WB) of anti-CD32C antibody
Western blot analysis of CD32c expression in HeLa (A); Raw264.7 (B); PC12 (C) whole cell lysates.
NCBI/Uniprot data below describe general gene information for CD32C. It may not necessarily be applicable to this product.
NCBI Accession #
NP_963857.3
[Other Products]
NCBI GenBank Nucleotide #
NM_201563.5
[Other Products]
UniProt Primary Accession #
P31995
[Other Products]
UniProt Secondary Accession #
O00523; O00524; O00525[Other Products]
UniProt Related Accession #
P31995[Other Products]
Molecular Weight
25,907 Da
NCBI Official Full Name
low affinity immunoglobulin gamma Fc region receptor II-c
NCBI Official Synonym Full Names
Fc fragment of IgG receptor IIc (gene/pseudogene)
NCBI Official Symbol
FCGR2C [Similar Products]
NCBI Official Synonym Symbols
CD32; FCG2; CD32C; CDW32; IGFR2; FCRIIC
[Similar Products]
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-c
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-c
UniProt Synonym Protein Names
CDw32; Fc-gamma RII-c; Fc-gamma-RIIc; FcRII-c; CD_antigen: CD32
UniProt Gene Name
FCGR2C [Similar Products]
UniProt Synonym Gene Names
CD32; FCG2; IGFR2; IgG Fc receptor II-c; Fc-gamma-RIIc; FcRII-c [Similar Products]
NCBI Summary for CD32C
This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants. [provided by RefSeq, Apr 2012]
UniProt Comments for CD32C
Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.CautionHas sometimes been attributed to correspond to FcR-IIB.
Research Articles on CD32C
1. When higher-affinity genotypes for FCGR2A, FCGR3A, and FCGR2C were considered together, they were associated with significantly increased tumor shrinkage and prolonged survival in response to HD-IL2... this is the first study to show associations of FCGR genotypes with outcome following HD-IL2 treatment
Precautions
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Disclaimer
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