Full Product Name
EMX2 Antibody
Product Gene Name
anti-EMX2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q04743
Species Reactivity
Human, Mouse
Concentration
1.0mg/ml (lot specific)
Other Notes
Small volumes of anti-EMX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-EMX2 antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for EMX2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001159396.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001165924.1
[Other Products]
UniProt Primary Accession #
Q04743
[Other Products]
UniProt Secondary Accession #
Q96NN8; Q9BQF4; G3V305[Other Products]
UniProt Related Accession #
Q04743[Other Products]
Molecular Weight
18,518 Da
NCBI Official Full Name
homeobox protein EMX2 isoform 2
NCBI Official Synonym Full Names
empty spiracles homeobox 2
NCBI Official Symbol
EMX2 [Similar Products]
NCBI Protein Information
homeobox protein EMX2
UniProt Protein Name
Homeobox protein EMX2
UniProt Synonym Protein Names
Empty spiracles homolog 2; Empty spiracles-like protein 2
Protein Family
Homeobox protein
UniProt Gene Name
EMX2 [Similar Products]
NCBI Summary for EMX2
This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and ***** olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.[provided by RefSeq, Sep 2009]
UniProt Comments for EMX2
Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
Research Articles on EMX2
1. EMX2 expression was down-regulated in lung SCC tissue compared to matched adjacent normal tissue. EMX2 expression was associated with improved overall survival. Knockdown promoted chemo-resistance and cell migration.
Precautions
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Disclaimer
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