Full Product Name
EDA Antibody
Product Synonym Names
EDA; ED1; EDA2; Ectodysplasin-A; Ectodermal dysplasia protein; EDA protein
Product Gene Name
anti-EDA antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q92838
Species Reactivity
Human, Mouse
Specificity
EDA Antibody detects endogenous levels of EDA protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human EDA.
Preparation and Storage
Store at -20 degree C for 1 year.
Other Notes
Small volumes of anti-EDA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-EDA antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Application Notes for anti-EDA antibody
WB: 1:500~1:2000
IHC-P: 1:100-1:300
ELISA: 1:10000
NCBI/Uniprot data below describe general gene information for EDA. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001005609.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001005609.1
[Other Products]
UniProt Primary Accession #
Q92838
[Other Products]
UniProt Secondary Accession #
O75910; Q5JS00; Q5JUM7; Q9UP77; Q9Y6L0; Q9Y6L1; Q9Y6L2; A0AUZ2; A2A337; B7ZLU2; B7ZLU4[Other Products]
UniProt Related Accession #
Q92838[Other Products]
NCBI Official Full Name
ectodysplasin-A isoform 2
NCBI Official Synonym Full Names
ectodysplasin A
NCBI Official Symbol
EDA [Similar Products]
NCBI Official Synonym Symbols
ED1; HED; EDA1; EDA2; HED1; ODT1; XHED; ECTD1; XLHED; ED1-A1; ED1-A2; EDA-A1; EDA-A2; TNLG7C; STHAGX1
[Similar Products]
NCBI Protein Information
ectodysplasin-A
UniProt Protein Name
Ectodysplasin-A
UniProt Synonym Protein Names
Ectodermal dysplasia protein; EDA protein
Protein Family
Ectodysplasin
UniProt Gene Name
EDA [Similar Products]
UniProt Synonym Gene Names
ED1; EDA2; EDA protein [Similar Products]
NCBI Summary for EDA
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for EDA
Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R (PubMed:8696334, PubMed:11039935, PubMed:27144394). May also play a role in cell adhesion ().
Research Articles on EDA
1. This is the first analysis of the role of Eda in the root, showing a direct role for this pathway during postnatal mouse development, and it suggests that changes in proliferation and angle of HERS may underlie taurodontism in a range of syndromes.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
