Full Product Name
AIF1 Antibody
Product Gene Name
anti-AIF1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P55008
Other Notes
Small volumes of anti-AIF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AIF1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001614.3
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NCBI GenBank Nucleotide #
NM_001623.4
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UniProt Primary Accession #
P55008
[Other Products]
UniProt Secondary Accession #
O43904; Q9UIV4; Q9UKS9; A8K406[Other Products]
UniProt Related Accession #
P55008[Other Products]
Molecular Weight
14,617 Da
NCBI Official Full Name
allograft inflammatory factor 1 isoform 3
NCBI Official Synonym Full Names
allograft inflammatory factor 1
NCBI Official Symbol
AIF1 [Similar Products]
NCBI Official Synonym Symbols
IBA1; IRT1; AIF-1; IRT-1
[Similar Products]
NCBI Protein Information
allograft inflammatory factor 1
UniProt Protein Name
Allograft inflammatory factor 1
UniProt Synonym Protein Names
Ionized calcium-binding adapter molecule 1; Protein G1
Protein Family
Apoptosis-inducing factor
UniProt Gene Name
AIF1 [Similar Products]
UniProt Synonym Gene Names
G1; IBA1; AIF-1 [Similar Products]
NCBI Summary for AIF1
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]
UniProt Comments for AIF1
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Research Articles on AIF1
1. This study shown the AIF1 expression in Microglia and Astrocytes in stroke, Alzheimer's disease, and Lewy body dementia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
