Full Product Name
SIX3 antibody - N-terminal region
Product Gene Name
anti-SIX3 antibody
[Similar Products]
Product Synonym Gene Name
HPE2[Similar Products]
Antibody/Peptide Pairs
SIX3 peptide (MBS3225928) is used for blocking the activity of SIX3 antibody (MBS3200891)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: VFRSPLDLYS SHFLLPNFAD SHHRSILLAS SGGGNGAGGG GGAGGGSGGG
3D Structure
ModBase 3D Structure for O95343
Species Reactivity
Cow, Dog, Human, Mouse, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 93%; Dog: 86%; Human: 100%; Mouse: 86%; Rat: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SIX3
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-SIX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SIX3 antibody
This is a rabbit polyclonal antibody against SIX3. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: SIX3 belongs to the SIX/Sine oculis homeobox family. It contains 1 homeobox DNA-binding domain. SIX3 may be involved in visual system development.
Product Categories/Family for anti-SIX3 antibody
Polyclonal; Transcription Factor; Neuro
biology; Transcription Regulation; Transcription Regulation; Developmental Biology; DNA/RNA/Protein Interactions; Transcription Factors;
Applications Tested/Suitable for anti-SIX3 antibody
Western Blot (WB)
Western Blot (WB) of anti-SIX3 antibody
WB Suggested Anti-SIX3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
NCBI/Uniprot data below describe general gene information for SIX3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005404
[Other Products]
NCBI GenBank Nucleotide #
NM_005413
[Other Products]
UniProt Primary Accession #
O95343
[Other Products]
UniProt Related Accession #
O95343[Other Products]
NCBI Official Full Name
homeobox protein SIX3
NCBI Official Synonym Full Names
SIX homeobox 3
NCBI Official Symbol
SIX3 [Similar Products]
NCBI Official Synonym Symbols
HPE2
[Similar Products]
NCBI Protein Information
homeobox protein SIX3
UniProt Protein Name
Homeobox protein SIX3
UniProt Synonym Protein Names
Sine oculis homeobox homolog 3
Protein Family
Homeobox protein
UniProt Gene Name
SIX3 [Similar Products]
UniProt Entry Name
SIX3_HUMAN
NCBI Summary for SIX3
This gene encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in this gene have been associated with holoprosencephaly type 2. [provided by RefSeq, Oct 2009]
Research Articles on SIX3
1. The authors demonstrate that the SIX3/LSD1/NuRD(MTA3) complex inhibits carcinogenesis in breast cancer cells and suppresses metastasis in breast cancer.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
