crystallin, gamma C, ELISA Kit

Human Gamma-crystallin C (CRYGC) ELISA kit; CCL; CRYG3; crystallin; gamma-3; crystallin; gamma C

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of CRYGC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9316700 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the crystallin, gamma C (CRYGC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CRYGC. The ELISA analytical biochemical technique of the MBS9316700 kit is based on CRYGC antibody-CRYGC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CRYGC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CRYGC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

20,879 Da

crystallin, gamma C

gamma-crystallin C; gamma-C-crystallin; gamma-crystallin 3; crystallin, gamma-3; gamma-crystallin 2-1

Gamma-crystallin C

CRYG3  [Similar Products]

CRGC_HUMAN

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]

CRYGC: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. Gamma-crystallins are involved in cataract formation.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 2q33.3

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; structural constituent of eye lens

Biological Process: camera-type eye development; visual perception

Disease: Cataract 2, Multiple Types

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