Product Name
Acyl-CoA-binding domain-containing protein 5 (ACBD5), Recombinant Protein
Full Product Name
Recombinant Human Acyl-CoA-binding domain-containing protein 5
Product Gene Name
ACBD5 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
Partial, 1-461aa
3D Structure
ModBase 3D Structure for Q5T8D3
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Other Notes
Small volumes of ACBD5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ACBD5 recombinant protein
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
NCBI/Uniprot data below describe general gene information for ACBD5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001035938.1
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NCBI GenBank Nucleotide #
NM_001042473.3
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UniProt Primary Accession #
Q5T8D3
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UniProt Secondary Accession #
Q5T8D4; Q5T8E1; Q5T8E2; Q86UV1; Q8N6E3; Q9UFB5; B3KQ56; D3DRW0[Other Products]
UniProt Related Accession #
Q5T8D3[Other Products]
NCBI Official Full Name
acyl-CoA-binding domain-containing protein 5 isoform 2
NCBI Official Synonym Full Names
acyl-CoA binding domain containing 5
NCBI Official Symbol
ACBD5 [Similar Products]
NCBI Protein Information
acyl-CoA-binding domain-containing protein 5
UniProt Protein Name
Acyl-CoA-binding domain-containing protein 5
Protein Family
Acyl-CoA-binding domain-containing protein
UniProt Gene Name
ACBD5 [Similar Products]
UniProt Synonym Gene Names
KIAA1996 [Similar Products]
NCBI Summary for ACBD5
This gene encodes a member of the acyl-Coenzyme A binding protein family, known to function in the transport and distribution of long chain acyl-Coenzyme A in cells. This gene may play a role in the differentiation of megakaryocytes and formation of platelets. A related protein in yeast is involved in autophagy of peroxisomes. A mutation in this gene has been associated with autosomal dominant thrombocytopenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
UniProt Comments for ACBD5
ACBD5: Binds medium- and long-chain acyl-CoA esters. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid-binding; Membrane protein, integral
Chromosomal Location of Human Ortholog: 10p12.1
Cellular Component: membrane; nucleoplasm; nucleus; peroxisomal membrane; peroxisome
Biological Process: fatty acid catabolic process; macroautophagy; peroxisome degradation
Research Articles on ACBD5
1. ACBD5 captures VLC-CoAs on the cytosolic side of the peroxisomal membrane so that the transport of VLC-CoAs into peroxisomes and subsequent beta-oxidation thereof can proceed efficiently.
Precautions
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Disclaimer
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