Product Name
Chymotrypsin (CTRC), Native Protein
Full Product Name
Chymotrypsin protein
Product Gene Name
CTRC native protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q99895
Purity/Purification
> 98% pure
Form/Format
Supplied as a lyophilised powder.
Source Note
Human pancreas
Biological Significance
Chymotrypsin is a digestive enzyme that can perform proteolysis. Chymotrypsin preferentially cleaves peptide amide bonds where the carboxyl side of the amide bond (the P1 position) is a tyrosine, tryptophan, or phenylalanine. Increased concentrations of this enzyme and/or its zymogen have been found in patients with cystic fibrosis.
Biohazard Information
Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
Preparation and Storage
Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of CTRC native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CTRC native protein
Purified native Human Chymotrypsin protein
Product Categories/Family for CTRC native protein
Proteases, Inhibitors, & Enzymes; Native Protein
Applications Tested/Suitable for CTRC native protein
User optimized
NCBI/Uniprot data below describe general gene information for CTRC. It may not necessarily be applicable to this product.
NCBI Accession #
CAA74031.1
[Other Products]
UniProt Primary Accession #
Q99895
[Other Products]
UniProt Secondary Accession #
O00765; Q9NUH5; A8K082[Other Products]
Molecular Weight
25 kDa[Similar Products]
NCBI Official Full Name
chymotrypsin, partial
UniProt Protein Name
Chymotrypsin-C
UniProt Synonym Protein Names
Caldecrin
Protein Family
Chymotrypsin
UniProt Gene Name
CTRC [Similar Products]
UniProt Synonym Gene Names
CLCR [Similar Products]
UniProt Entry Name
CTRC_HUMAN
UniProt Comments for CTRC
CTRC: Has chymotrypsin-type protease activity and hypocalcemic activity. Genetic variations in CTRC can predispose to chronic pancreatitis by diminishing its protective trypsin-degrading activity. Belongs to the peptidase S1 family. Elastase subfamily.
Protein type: EC 3.4.21.2; Protease
Chromosomal Location of Human Ortholog: 1p36.21
Molecular Function: peptidase activity; serine-type endopeptidase activity
Biological Process: proteolysis
Disease: Pancreatitis, Hereditary
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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