hyaluronidase 1, Blocking Peptide

hyaluronoglucosaminidase 1; Hyal; Hyal-1; hyaluronidase 1; Hyaluronidase 1; hyaluronidase 1 (mouse, rat)

For Research Use Only. Not for use in diagnostic procedures.

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

Manufactured in an ISO 9001:2008 Certified Laboratory.

Small volumes of HYAL1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

51,436 Da

hyaluronoglucosaminidase 1

hyaluronidase-1

Hyaluronidase-1

Hyal-1  [Similar Products]

HYAL1_MOUSE

HYAL1: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth. Defects in HYAL1 are the cause of mucopolysaccharidosis type 9 (MPS9); also called hyaluronidase deficiency. MPS9 is a lysosomal storage disease characterized by high hyaluronan (HA) concentration in the serum. The clinical features are periarticular soft tissue masses, mild short stature and acetabular erosions, and absence of neurological or visceral involvement. Belongs to the glycosyl hydrolase 56 family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Secreted; Secreted, signal peptide; Glycan Metabolism - glycosaminoglycan degradation; EC 3.2.1.35

Cellular Component: cytoplasm; cytoplasmic vesicle; extracellular region; extracellular space; lysosome

Molecular Function: catalytic activity; hyaluronan synthase activity; hyalurononglucosaminidase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; transcription factor binding; viral receptor activity

Biological Process: carbohydrate metabolic process; hyaluronan biosynthetic process; hyaluronan catabolic process; hyaluronan metabolic process; inflammatory response; metabolic process; negative regulation of cell growth; positive regulation of angiogenesis; positive regulation of cell adhesion; positive regulation of cell growth; positive regulation of epithelial cell proliferation; positive regulation of growth; response to antibiotic; response to reactive oxygen species; response to virus

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