Full Product Name
CABP4 Antibody, Biotin conjugated
Product Synonym Names
Calcium-binding protein 4; CaBP4; CABP4
Product Gene Name
anti-CABP4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P57796
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Calcium-binding protein 4 protein (1-107AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-CABP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CABP4 antibody
Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages (By similarity).
Product Categories/Family for anti-CABP4 antibody
Neuroscience; Signal transduction
Applications Tested/Suitable for anti-CABP4 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for CABP4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001287824.1
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NCBI GenBank Nucleotide #
NM_001300895.1
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UniProt Primary Accession #
P57796
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UniProt Secondary Accession #
Q8N4Z2; Q8WWY5[Other Products]
UniProt Related Accession #
P57796[Other Products]
Molecular Weight
19,600 Da
NCBI Official Full Name
calcium-binding protein 4 isoform b
NCBI Official Synonym Full Names
calcium binding protein 4
NCBI Official Symbol
CABP4 [Similar Products]
NCBI Official Synonym Symbols
CRSD; CSNB2B
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NCBI Protein Information
calcium-binding protein 4
UniProt Protein Name
Calcium-binding protein 4
Protein Family
Calcium-binding protein
UniProt Gene Name
CABP4 [Similar Products]
UniProt Synonym Gene Names
CaBP4 [Similar Products]
NCBI Summary for CABP4
This gene encodes a member of the CABP family of calcium binding protein characterized by four EF-hand motifs. Mutations in this gene are associated with congenital stationary night blindness type 2B. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
UniProt Comments for CABP4
Involved in normal synaptic function through regulation of Ca2+ influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages ().
Research Articles on CABP4
1. Foveal thinning is a feature of CABP4 retinopathy. Normal autofluorescence is consistent with inner retinal dysfunction and suggests the condition could be amenable to gene therapy. Retinal dysfunction was stable throughout follow-up.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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