Product Name
ACADS, Peptide
Full Product Name
ACADS Blocking Peptide
Product Gene Name
ACADS peptide
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P15651
Form/Format
50 ug (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Appearance: Colorless liquid
Concentration
0.5 mg/ml (lot specific)
Handling
The peptide solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Other Notes
Small volumes of ACADS peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for ACADS peptide
Antibodies & Supporting Tools; Blocking Peptides
Applications Tested/Suitable for ACADS peptide
Western Blot (WB)
Application Notes for ACADS peptide
The peptide is used for blocking the antibody activity of ACADS. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37 degree C.
NCBI/Uniprot data below describe general gene information for ACADS. It may not necessarily be applicable to this product.
NCBI Accession #
NP_071957.1
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NCBI GenBank Nucleotide #
NM_022512.2
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UniProt Primary Accession #
P15651
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UniProt Related Accession #
P15651[Other Products]
Molecular Weight
44,765 Da
NCBI Official Full Name
short-chain specific acyl-CoA dehydrogenase, mitochondrial
NCBI Official Synonym Full Names
acyl-CoA dehydrogenase, C-2 to C-3 short chain
NCBI Official Symbol
Acads [Similar Products]
NCBI Official Synonym Symbols
Scad
[Similar Products]
NCBI Protein Information
short-chain specific acyl-CoA dehydrogenase, mitochondrial
UniProt Protein Name
Short-chain specific acyl-CoA dehydrogenase, mitochondrial
UniProt Synonym Protein Names
Butyryl-CoA dehydrogenase
Protein Family
Short-chain specific acyl-CoA dehydrogenase
UniProt Gene Name
Acads [Similar Products]
UniProt Synonym Gene Names
SCAD [Similar Products]
UniProt Entry Name
ACADS_RAT
UniProt Comments for ACADS
ACADS: Defects in ACADS are the cause of acyl-CoA dehydrogenase short-chain deficiency (ACADSD). It is an autosomal recessive disorder resulting in acute acidosis and muscle weakness in infants, and a form of lipid-storage myopathy in *****s. Belongs to the acyl-CoA dehydrogenase family.
Protein type: Mitochondrial; Lipid-binding; Oxidoreductase; EC 1.3.8.1; Lipid Metabolism - fatty acid; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - valine, leucine and isoleucine degradation
Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial membrane; nucleus
Molecular Function: acyl-CoA dehydrogenase activity; butyryl-CoA dehydrogenase activity; FAD binding; acyl-CoA binding
Biological Process: response to starvation; fatty acid beta-oxidation; response to glucocorticoid stimulus; fatty acid beta-oxidation using acyl-CoA dehydrogenase; protein homotetramerization; butyrate catabolic process
Research Articles on ACADS
1. the phosphorylation of ERK1/2 inhibited the expression and activity of SCAD through the PPARalpha signaling pathway, which induced the development of pathological cardiomyocyte hypertrophy.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
