Product Name
ATP-binding cassette sub-family G member 5 (Abcg5), Recombinant Protein
Full Product Name
Recombinant Rat ATP-binding cassette sub-family G member 5 (Abcg5), partial
Product Gene Name
Abcg5 recombinant protein
[Similar Products]
Product Synonym Gene Name
Abcg5[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q99PE7
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rattus norvegicus (Rat)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Abcg5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Abcg5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_446206.2
[Other Products]
NCBI GenBank Nucleotide #
NM_053754.2
[Other Products]
UniProt Primary Accession #
Q99PE7
[Other Products]
UniProt Secondary Accession #
Q8CIQ4[Other Products]
UniProt Related Accession #
Q99PE7[Other Products]
Molecular Weight
73,372 Da
NCBI Official Full Name
ATP-binding cassette sub-family G member 5
NCBI Official Synonym Full Names
ATP binding cassette subfamily G member 5
NCBI Official Symbol
Abcg5 [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family G member 5
UniProt Protein Name
ATP-binding cassette sub-family G member 5
UniProt Synonym Protein Names
Sterolin-1
Protein Family
ABC transporter G family
UniProt Gene Name
Abcg5 [Similar Products]
NCBI Summary for Abcg5
ATP-transporter family member that may regulate absorption of dietary cholesterol; human homolog is mutated in sitosterolemia, a disease of hyperabsorption of cholesterol and other sterols [RGD, Feb 2006]
UniProt Comments for Abcg5
ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg2+- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG8 has ATPase activity.
Research Articles on Abcg5
1. In contrast, the marked reduction of hepatic Abcg5/8 observed is an effect of the high sugar content of the diets.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
