Full Product Name
CETP, NT (Lipid Transfer Protein I, Cholesteryl Ester Transfer Protein)
Product Synonym Names
Anti -CETP, NT (Lipid Transfer Protein I, Cholesteryl Ester Transfer Protein)
Product Gene Name
anti-CETP antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 16; NC_000016.9 (56995835..57017756). Location: 16q21
3D Structure
ModBase 3D Structure for P11597
Specificity
Recognizes human CETP.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Immunogen
Synthetic peptide selected from the N-terminal region of human CETP (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-CETP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CETP antibody
Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. CETP may effect susceptibility to atherosclerosis.
Product Categories/Family for anti-CETP antibody
Antibodies; Abs to Serum Proteins
Applications Tested/Suitable for anti-CETP antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CETP antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
NCBI/Uniprot data below describe general gene information for CETP. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000069.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000078.2
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UniProt Primary Accession #
P11597
[Other Products]
UniProt Secondary Accession #
Q13987; Q13988; Q53YZ1[Other Products]
UniProt Related Accession #
P11597; Q5TZS4; Q8IWL9; Q9H4L8[Other Products]
Molecular Weight
54,756 Da[Similar Products]
NCBI Official Full Name
cholesteryl ester transfer protein
NCBI Official Synonym Full Names
cholesteryl ester transfer protein, plasma
NCBI Official Symbol
CETP [Similar Products]
NCBI Official Synonym Symbols
HDLCQ10
[Similar Products]
NCBI Protein Information
cholesteryl ester transfer protein; OTTHUMP00000164380; lipid transfer protein I
UniProt Protein Name
Cholesteryl ester transfer protein
UniProt Synonym Protein Names
Lipid transfer protein I
Protein Family
Cholesteryl ester transfer protein
UniProt Gene Name
CETP [Similar Products]
UniProt Entry Name
CETP_HUMAN
NCBI Summary for CETP
Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. CETP may effect susceptibility to atherosclerosis. [provided by RefSeq]
UniProt Comments for CETP
CETP: Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. Defects in CETP are the cause of hyperalphalipoproteinemia type 1 (HALP1). Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL). Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Lipid-binding; Vesicle; Secreted
Chromosomal Location of Human Ortholog: 16q21
Cellular Component: extracellular space; extracellular region; vesicle
Molecular Function: lipid transporter activity; phospholipid transporter activity; cholesterol transporter activity; cholesterol binding; phosphatidylcholine binding; lipid binding; triglyceride binding
Biological Process: cholesterol metabolic process; receptor-mediated endocytosis; cholesterol transport; lipid homeostasis; lipoprotein metabolic process; lipid transport; phosphatidylcholine metabolic process; cholesterol homeostasis; reverse cholesterol transport; triacylglycerol metabolic process; phospholipid transport; triacylglycerol transport; transmembrane transport; phospholipid homeostasis
Disease: Hyperalphalipoproteinemia 1
Research Articles on CETP
1. Polymorphisms of the ABCA1 and CETP genes are associated with altered plasma HDL-C concentrations.These associations on HDL-C levels are modified by BMI in a Chinese population of the Chengdu area.
Precautions
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Disclaimer
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