Product Name
MeCP2, Blocking Peptide
Full Product Name
MeCP2 Antibody (C-term) Blocking Peptide
Product Synonym Names
Methyl-CpG-binding protein 2; MeCp-2 protein; MeCp2; MECP2
Product Gene Name
MECP2 blocking peptide
[Similar Products]
Antibody/Peptide Pairs
MeCP2 peptide (MBS9224717) is used for blocking the activity of MeCP2 antibody (MBS9213921)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q95LG8
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human MeCP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Cellular Location
Nucleus. Note: Colocalized with methyl-CpG in the genome.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of MECP2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
MECP2 blocking peptide
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC) (By similarity).
NCBI/Uniprot data below describe general gene information for MECP2. It may not necessarily be applicable to this product.
NCBI Accession #
Q95LG8.1
[Other Products]
UniProt Primary Accession #
Q95LG8
[Other Products]
UniProt Related Accession #
Q95LG8[Other Products]
Molecular Weight
52,427 Da
NCBI Official Full Name
Methyl-CpG-binding protein 2
NCBI Official Symbol
MECP2 [Similar Products]
NCBI Protein Information
methyl-CpG-binding protein 2
UniProt Protein Name
Methyl-CpG-binding protein 2
Protein Family
Methyl-CpG-binding protein
UniProt Gene Name
MECP2 [Similar Products]
UniProt Synonym Gene Names
MeCp-2 protein; MeCp2 [Similar Products]
UniProt Entry Name
MECP2_MACFA
UniProt Comments for MECP2
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
