Full Product Name
DCTN4 Antibody
Product Gene Name
anti-DCTN4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of DCTN4
Calculated Molecular Weight: 460aa; 52kd
Observed Molecular Weight: 62kd
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-12239 / sc-12241 / sc-25730
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-DCTN4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-DCTN4 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-DCTN4 antibody
WB: 1:500-1:5000
Testing Data of anti-DCTN4 antibody
NCBI/Uniprot data below describe general gene information for DCTN4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001129116.1
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NCBI GenBank Nucleotide #
NM_001135644.1
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UniProt Secondary Accession #
Q8TAN8; B3KWW0; D3DQH0; E5RGT5[Other Products]
UniProt Related Accession #
Q9UJW0[Other Products]
Molecular Weight
53,152 Da
NCBI Official Full Name
dynactin subunit 4 isoform c
NCBI Official Synonym Full Names
dynactin 4 (p62)
NCBI Official Symbol
DCTN4 [Similar Products]
NCBI Official Synonym Symbols
P62; DYN4
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NCBI Protein Information
dynactin subunit 4; dynactin p62 subunit; dynactin subunit p62
UniProt Protein Name
Dynactin subunit 4
UniProt Synonym Protein Names
Dynactin subunit p62
UniProt Gene Name
DCTN4 [Similar Products]
UniProt Synonym Gene Names
Dyn4 [Similar Products]
UniProt Entry Name
DCTN4_HUMAN
UniProt Comments for DCTN4
dynactin 4: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Belongs to the dynactin subunit 4 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Microtubule-binding; Motor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q33.1
Cellular Component: centrosome; dynactin complex; cytoplasmic dynein complex; cytoplasm; cytosol; nucleus
Molecular Function: protein N-terminus binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; nuclear migration
Research Articles on DCTN4
1. used an extreme phenotype study to discover that variants in DCTN4, encoding a dynactin protein, are associated with time to first P. aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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