Full Product Name
LAMA2 Antibody, Biotin conjugated
Product Synonym Names
Laminin subunit alpha-2; Laminin M chain; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; Merosin heavy chain; LAMA2; LAMM
Product Gene Name
anti-LAMA2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P24043
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Laminin subunit alpha-2 protein (974-1162AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-LAMA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-LAMA2 antibody
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Product Categories/Family for anti-LAMA2 antibody
Neuroscience; Cardiovascular; Signal transduction
Applications Tested/Suitable for anti-LAMA2 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for LAMA2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000417.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000426.3
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UniProt Primary Accession #
P24043
[Other Products]
UniProt Secondary Accession #
Q14736; Q5VUM2; Q93022[Other Products]
UniProt Related Accession #
P24043[Other Products]
Molecular Weight
343,905 Da
NCBI Official Full Name
laminin subunit alpha-2 isoform a
NCBI Official Synonym Full Names
laminin subunit alpha 2
NCBI Official Symbol
LAMA2 [Similar Products]
NCBI Official Synonym Symbols
LAMM
[Similar Products]
NCBI Protein Information
laminin subunit alpha-2
UniProt Protein Name
Laminin subunit alpha-2
UniProt Synonym Protein Names
Laminin M chain; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; Merosin heavy chain
UniProt Gene Name
LAMA2 [Similar Products]
UniProt Synonym Gene Names
LAMM [Similar Products]
NCBI Summary for LAMA2
Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for LAMA2
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Research Articles on LAMA2
1. It was established that the frequency of individuals with the COL13A1*D/*D genotype was higher in the senile age period. The LAMA2*I/*D genotype was predisposing to longevity among women.
Precautions
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Disclaimer
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