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ATAD5 / FRAG1, Blocking Peptide

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产品名称: ATAD5 / FRAG1, Blocking Peptide
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简单介绍

ATAD5 / FRAG1, Blocking Peptide


ATAD5 / FRAG1, Blocking Peptide  的详细介绍
Product Name

ATAD5 / FRAG1, Blocking Peptide

Full Product Name

ATAD5 / FRAG1 Immunizing Peptide

Product Synonym Names
ATAD5; C17orf41; chromosome 17 open reading frame 41; FLJ12735; FRAG1; chromosome fragility associated gene 1; ATPase family, AAA domain containing 5; ATAD5 / FRAG1
Product Gene Name

ATAD5 blocking peptide

[Similar Products]
Product Synonym Gene Name
FRAG1[Similar Products]
Antibody/Peptide Pairs
ATAD5 / FRAG1 peptide (MBS425736) is used for blocking the activity of ATAD5/FRAG1 antibody (MBS420012)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence
C-DNKIYPKN TKKKRVD
OMIM
609534
Species Reactivity
Human
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ATAD5 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ATAD5. It may not necessarily be applicable to this product.
NCBI GI #
26080431
NCBI GeneID
79915
NCBI Accession #
NP_079133.3 [Other Products]
NCBI GenBank Nucleotide #
NM_024857.4 [Other Products]
UniProt Secondary Accession #
Q05DH0; Q69YR6; Q9H9I1[Other Products]
UniProt Related Accession #
Q96QE3[Other Products]
Molecular Weight
135,878 Da
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NCBI Official Full Name
ATPase family AAA domain-containing protein 5
NCBI Official Synonym Full Names
ATPase family, AAA domain containing 5
NCBI Official Symbol
ATAD5  [Similar Products]
NCBI Official Synonym Symbols
ELG1; FRAG1; C17orf41
  [Similar Products]
NCBI Protein Information
ATPase family AAA domain-containing protein 5
UniProt Protein Name
ATPase family AAA domain-containing protein 5
UniProt Synonym Protein Names
Chromosome fragility-associated gene 1 protein
Protein Family
ATPase family AAA domain-containing protein
UniProt Gene Name
ATAD5  [Similar Products]
UniProt Synonym Gene Names
C17orf41; FRAG1  [Similar Products]
UniProt Entry Name
ATAD5_HUMAN
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UniProt Comments for ATAD5
ATAD5: Involved in DNA damage response. Involved in a RAD9A- related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages- induced apoptosis. Belongs to the AAA ATPase family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: nucleus

Molecular Function: ATP binding

Biological Process: response to DNA damage stimulus
Research Articles on ATAD5
1. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review]
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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