Product Name
CYP7B1, Polyclonal Antibody
Full Product Name
Mouse Cyp7b1 Polyclonal Antibody
Product Synonym Names
Cytochrome P450 7B1; Hippocampal transcript 1 protein; Oxysterol 7-alpha-hydroxylase; HCT-1
Product Gene Name
anti-CYP7B1 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse
Purity/Purification
Immunogen Affinity Purified
Form/Format
Liquid; 0.1MxPBS, 50% Glycerol, pH7.5
Concentration
200 ug/ml (lot specific)
Immunogen
Recombinant Human Cyp7b1 Protein
Preparation and Storage
Store at 4 degree C for frequent use. Store at -20 degree C to -70 degree C for 6 months.
Other Notes
Small volumes of anti-CYP7B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CYP7B1 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for CYP7B1. It may not necessarily be applicable to this product.
UniProt Related Accession #
O75881[Other Products]
NCBI Official Full Name
CYP7B1 protein, partial
NCBI Official Synonym Full Names
cytochrome P450 family 7 subfamily B member 1
NCBI Official Symbol
CYP7B1 [Similar Products]
NCBI Official Synonym Symbols
CP7B; CBAS3; SPG5A
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NCBI Protein Information
25-hydroxycholesterol 7-alpha-hydroxylase
Protein Family
25-hydroxycholesterol 7-alpha-hydroxylase
NCBI Summary for CYP7B1
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]
Research Articles on CYP7B1
1. SPG11 and CYP7B1 were the most common cause of autosomal recessive hereditary spastic paraplegia in Greece.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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