Full Product Name
GJA9 Antibody
Product Synonym Names
gap junction protein, alpha 9, 59kDa, CX58, CX59, GJA10
Product Gene Name
anti-GJA9 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Specificity
The antibody detects endogenous level of total GJA9 protein.
Form/Format
Supplied at 0.8mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Immunogen Description
Synthetic peptide corresponding to a region derived from 246-260 amino acids of Human gap junction protein, alpha 9, 59kDa
Preparation and Storage
Store at -20 degree C/1 year
Other Notes
Small volumes of anti-GJA9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GJA9 antibody
Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Product Categories/Family for anti-GJA9 antibody
Total protein Ab
Applications Tested/Suitable for anti-GJA9 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-GJA9 antibody
ELISA: 1:1000-1:5000
Western blotting: 1:2000-1:5000
Testing Data of anti-GJA9 antibody
Gel: 8%SDS-PAGELane1: Human fetal muscle tissue lysateLane2: OP9 cell lysateLysates: 40 ug per lanePrimary antibody: 1/400 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutionExposure time: 1 minute
NCBI/Uniprot data below describe general gene information for GJA9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_110399
[Other Products]
NCBI GenBank Nucleotide #
NM_030772.4
[Other Products]
UniProt Secondary Accession #
Q5TA63; Q96KG0; B2R722; B3KVQ2[Other Products]
UniProt Related Accession #
P57773[Other Products]
Molecular Weight
58,950 Da
NCBI Official Full Name
gap junction alpha-9 protein
NCBI Official Synonym Full Names
gap junction protein, alpha 9, 59kDa
NCBI Official Symbol
GJA9 [Similar Products]
NCBI Official Synonym Symbols
CX58; CX59; GJA10
[Similar Products]
NCBI Protein Information
gap junction alpha-9 protein
UniProt Protein Name
Gap junction alpha-9 protein
UniProt Synonym Protein Names
Connexin-58; Cx58; Connexin-59; Cx59; Gap junction alpha-10 protein
Protein Family
Gap junction alpha-9 protein
UniProt Gene Name
GJA9 [Similar Products]
UniProt Synonym Gene Names
GJA10; Cx58; Cx59 [Similar Products]
UniProt Entry Name
CXA9_HUMAN
NCBI Summary for GJA9
Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008]
UniProt Comments for GJA9
GJA9: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Alpha-type (group II) subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p34
Cellular Component: connexon complex; integral to membrane
Biological Process: cell communication
Research Articles on GJA9
1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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