Full Product Name
P3H1 Antibody - middle region
Product Gene Name
anti-P3H1 antibody
[Similar Products]
Product Synonym Gene Name
OI8; GROS1; LEPRE1[Similar Products]
Antibody/Peptide Pairs
P3H1 peptide (MBS3247156) is used for blocking the activity of P3H1 antibody (MBS3222488)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: RLTNVAATSG DGYRGQTSPH TPNEKFYGVT VFKALKLGQE GKVPLQSAHL
3D Structure
ModBase 3D Structure for Q32P28
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human LEPRE1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-P3H1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-P3H1 antibody
This gene encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Three alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their
biological validity has not been determined.
Product Categories/Family for anti-P3H1 antibody
Polyclonal; Disease Related;
Applications Tested/Suitable for anti-P3H1 antibody
Western Blot (WB)
Western Blot (WB) of anti-P3H1 antibody
Host: Rabbit
Target Name: LEPRE1
Sample Tissue: Human HepG2 Whole Cell lysates
Antibody Dilution: 1ug/ml

NCBI/Uniprot data below describe general gene information for P3H1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001139761.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001146289.1
[Other Products]
UniProt Primary Accession #
Q32P28
[Other Products]
UniProt Related Accession #
Q32P28[Other Products]
NCBI Official Full Name
prolyl 3-hydroxylase 1 isoform 2
NCBI Official Synonym Full Names
prolyl 3-hydroxylase 1
NCBI Official Symbol
P3H1 [Similar Products]
NCBI Official Synonym Symbols
OI8; GROS1; LEPRE1
[Similar Products]
NCBI Protein Information
prolyl 3-hydroxylase 1
UniProt Protein Name
Prolyl 3-hydroxylase 1
UniProt Synonym Protein Names
Growth suppressor 1; Leucine- and proline-enriched proteoglycan 1
Protein Family
Prolyl 3-hydroxylase
UniProt Gene Name
LEPRE1 [Similar Products]
UniProt Synonym Gene Names
GROS1; P3H1 [Similar Products]
UniProt Entry Name
P3H1_HUMAN
NCBI Summary for P3H1
This gene encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Three alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their biological validity has not been determined. [provided by RefSeq, Aug 2011]
Research Articles on P3H1
1. P3H1 mutation is associated with Non-Lethal Type VIII Osteogenesis Imperfecta.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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