Full Product Name
ISPD Antibody - middle region
Product Gene Name
anti-ISPD antibody
[Similar Products]
Product Synonym Gene Name
AV040780; 4930579E17Rik[Similar Products]
Antibody/Peptide Pairs
ISPD peptide (MBS3248330) is used for blocking the activity of ISPD antibody (MBS3223721)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: DIVVTVTGEN MEAMRSIIQR YGHKRISLAE AGATRHRSIF NGLKALAEDQ
3D Structure
ModBase 3D Structure for Q5RJG7
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 8% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of mouse ISPD
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -26C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ISPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ISPD antibody
Cytidylyltransferase required for protein O-linked mannosylation. Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate. CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively. Not Involved in dolichol production.
Product Categories/Family for anti-ISPD antibody
Polyclonal; Cell Biology;
Applications Tested/Suitable for anti-ISPD antibody
Western Blot (WB)
Western Blot (WB) of anti-ISPD antibody
Host: Rabbit
Target Name: ISPD
Sample Tissue: Mouse Pancreas lysates
Antibody Dilution: 1ug/ml
NCBI/Uniprot data below describe general gene information for ISPD. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001276431.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001289502.1
[Other Products]
UniProt Primary Accession #
Q5RJG7
[Other Products]
UniProt Related Accession #
Q5RJG7[Other Products]
NCBI Official Full Name
D-ribitol-5-phosphate cytidylyltransferase isoform 2
NCBI Official Synonym Full Names
CDP-L-ribitol pyrophosphorylase A
NCBI Official Symbol
Crppa [Similar Products]
NCBI Official Synonym Symbols
Ispd; AV040780; 4930579E17Rik
[Similar Products]
NCBI Protein Information
D-ribitol-5-phosphate cytidylyltransferase; isoprenoid synthase domain-containing protein
UniProt Protein Name
D-ribitol-5-phosphate cytidylyltransferase
UniProt Synonym Protein Names
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein
Protein Family
Isoprenoid synthase domain-containing protein
UniProt Gene Name
Ispd [Similar Products]
UniProt Comments for ISPD
Cytidylyltransferase required for protein O-linked mannosylation. Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate. CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively. Not Involved in dolichol production.
Research Articles on ISPD
1. we show that activated NOTCH1 and ZMIZ1 collaborate to induce T-ALL in mice
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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