Product Name
SLC25A38, Polyclonal Antibody
Popular Item
Full Product Name
SLC25A38 Polyclonal Antibody
Product Synonym Names
SIDBA2
Product Gene Name
anti-SLC25A38 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
CMSPITVIKT RYESGKYGYE SIYAALRSIY HSEGHRGLFS GLTATLLRDA PFSGIYLMFY NQTKNIVPHD QVDATLIPIT N
3D Structure
ModBase 3D Structure for Q96DW6
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human SLC25A38
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Mitochondrion inner membrane, Multi-pass membrane protein
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-SLC25A38 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC25A38 antibody
This gene is a member of the mitochondrial carrier family. The encoded protein is required during erythropoiesis and is important for the biosynthesis of heme. Mutations in this gene are the cause of autosomal congenital sideroblastic anemia.
Product Categories/Family for anti-SLC25A38 antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-SLC25A38 antibody
Western Blot (WB)
Application Notes for anti-SLC25A38 antibody
WB: 1:500 - 1:2000
Western Blot (WB) of anti-SLC25A38 antibody
Western blot analysis of extracts of 293T cells, using SLC25A38 antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
NCBI/Uniprot data below describe general gene information for SLC25A38. It may not necessarily be applicable to this product.
NCBI Accession #
NP_060345.2
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NCBI GenBank Nucleotide #
NM_017875.3
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UniProt Primary Accession #
Q96DW6
[Other Products]
UniProt Secondary Accession #
Q9NWX2[Other Products]
UniProt Related Accession #
Q96DW6[Other Products]
Molecular Weight
Calculated: 33kDa
Observed: 33kDa
NCBI Official Full Name
solute carrier family 25 member 38 isoform 1
NCBI Official Synonym Full Names
solute carrier family 25 member 38
NCBI Official Symbol
SLC25A38 [Similar Products]
NCBI Official Synonym Symbols
SIDBA2
[Similar Products]
NCBI Protein Information
solute carrier family 25 member 38
UniProt Protein Name
Solute carrier family 25 member 38
Protein Family
Solute carrier family
UniProt Gene Name
SLC25A38 [Similar Products]
NCBI Summary for SLC25A38
This gene is a member of the mitochondrial carrier family. The encoded protein is required during erythropoiesis and is important for the biosynthesis of heme. Mutations in this gene are the cause of autosomal congenital sideroblastic anemia (anemia, sideroblastic, 2, pyridoxine-refractory). A related pseudogene is found on chromosome 1. [provided by RefSeq, Aug 2017]
UniProt Comments for SLC25A38
Mitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane.
Research Articles on SLC25A38
1. the biochemical and molecular characterization of yeast Hem25p and human SLC25A38, providing evidence that they are mitochondrial carriers for glycine. In particular, the hem25Delta mutant manifests a defect in the biosynthesis of delta-aminolevulinic acid and displays reduced levels of downstream heme and mitochondrial cytochromes.
Precautions
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Disclaimer
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