Product Name
TBX22, cDNA Clone
Full Product Name
TBX22 cDNA Clone
Product Gene Name
TBX22 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggctctga gctctcgggc gcgtgccttc tccgtggaag ccttggtggg gagacccagc aaaagaaaac tccaagaccc aatacaggcg gagcagcctg agctgcggga gaaaaagggc ggagaggaag aggaggagag aaggagcagc gctgcaggga agagcgagcc gcttgaaaaa caacctaaga cagagccctc aacatctgct tcctctggct gcggcagcga cagcggctac ggcaacagct ctgaaagtct ggaagagaaa gatattcaaa tggagcttca aggatctgaa ctgtggaaaa gattccatga catcgggact gagatgatca ttactaaagc gggcaggcgg atgttcccct ctgttcgggt caaggtgaaa gggttggatc cagggaagca gtaccatgtg gccatcgatg tggtgccggt ggattccaaa cgctataggt acgtctatca cagctcacag tggatggtag ctgggaatac agaccatttg tgcatcattc ctagattcta tgttcacccg gactcaccct gctcgggaga gacctggatg cggcagatca tcagctttga tcgcatgaaa ctcaccaaca atgagatgga tgacaaaggc cacatcattc tgcaatccat gcataagtac aaaccccgag tgcacgtgat agagcaaggc agcagtgttg acctgtccca gattcagtcc ttgcccactg aaggtgttaa aacattctcc tttaaagaaa ctgagttcac cacagtaacg gcttaccaaa accaacagat tacgaaacta aaaatagaaa gaaatccttt tgctaaagga tttagagata ctggaagaaa caggggtgta ttggatgggc ttttagagac ctacccatgg aggccttctt tcactctcga ttttaaaacc tttggcgcag acacacaaag tggaagcagt ggctcatctc cagtgacctc tagtggaggg gccccctctc ctttgaactc cttactttct ccactttgct tttcacctat gtttcattta cctacaagct cccttggaat gccctgtcca gaggcatacc tgcccaatgt caacctgcct ctatgctaca agatttgtcc aactaatttt tggcaacagc aacctcttgt tttaccggct cctgaaagac tagcaagcag caacagttct cagtctttag ccccactcat gatggaagtg cctatgttat cttccctggg ggtcaccaat tcaaaaagcg gttcatctga agactccagt gatcagtatc tacaagcacc taattctacc aatcaaatgt tatatggatt acagtcacct ggaaatattt ttctgccaaa ctccatcacc ccagaagcac ttagttgctc ctttcatcct tcctatgact tttatagata caatttctct atgccatcta gactgataag tggttccaac catcttaaag tgaatgacga cagtcaagtt tcttttggag aaggcaaatg taatcatgtt cattggtatc cagcaattaa ccattacctt tag
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of TBX22 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TBX22. It may not necessarily be applicable to this product.
NCBI Accession #
BC014194
[Other Products]
UniProt Secondary Accession #
Q5JZ06; Q96LC0; Q9HBF1[Other Products]
UniProt Related Accession #
Q9Y458[Other Products]
Molecular Weight
44,718 Da
NCBI Official Full Name
Homo sapiens T-box 22, mRNA
NCBI Official Synonym Full Names
T-box 22
NCBI Official Symbol
TBX22 [Similar Products]
NCBI Official Synonym Symbols
CPX; CLPA; TBXX; ABERS; dJ795G23.1
[Similar Products]
NCBI Protein Information
T-box transcription factor TBX22
UniProt Protein Name
T-box transcription factor TBX22
Protein Family
T-box transcription factor
UniProt Gene Name
TBX22 [Similar Products]
UniProt Synonym Gene Names
TBOX22; T-box protein 22 [Similar Products]
UniProt Entry Name
TBX22_HUMAN
NCBI Summary for TBX22
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for TBX22
TBX22: Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis. Defects in TBX22 are the cause of X-linked cleft palate with ankyloglossia (CPX). 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: Xq21.1
Cellular Component: nucleus
Molecular Function: DNA binding; protein binding; transcription factor activity
Biological Process: multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent
Disease: Abruzzo-erickson Syndrome; Cleft Palate With Or Without Ankyloglossia, X-linked
Research Articles on TBX22
1. we analysed two TBX22 promoter rs7055763 and rs41307258 single-nucleotide polymorphisms (SNPs) in 173 patients with NSCLP and 176 normal controls of south Indian origin using Kbioscience KASPar chemistry
Precautions
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Disclaimer
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