KMT2D/MLL2, Monoclonal Antibody

Goat Polyclonal to Human KMT2D/MLL2; KMT2D; AAD10; ALL1-related protein; KABUK1; KMS; Lysine N-methyltransferase 2D; MLL2; Kabuki make-up syndrome; ALR; CAGL114; KMT2B; Lysine N-methyltransferase 2B; TNRC21

For Research Use Only. Not for use in diagnostic procedures.

Monoclonal

IgG2a, k

2E1

Mouse

Human MLL2

Purified from ascites by Protein A

PBS, pH 7.4.

Store at -20 degree C or lower.
Aliquot to avoid repeated freezing and thawing.

Small volumes of anti-KMT2D/MLL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me).H3K4me represents a specific tag for epigenetic transcriptionalactivation. Acts as a coactivator for estrogen receptor by beingrecruited by ESR1, thereby activating transcription.

ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)

IHC-P: 10 ug/ml

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

593,677 Da

lysine methyltransferase 2D

histone-lysine N-methyltransferase 2D

Histone-lysine N-methyltransferase 2D

ALR; MLL2; MLL4; Lysine N-methyltransferase 2D  [Similar Products]

The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010]

Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.

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