Product Name
GABRR2, Polyclonal Antibody
Full Product Name
GABRR2 antibody - middle region
Product Gene Name
anti-GABRR2 antibody
[Similar Products]
Antibody/Peptide Pairs
GABRR2 peptide (MBS3227394) is used for blocking the activity of GABRR2 antibody (MBS3202416)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: SNKSMTFDGR LVKKIWVPDV FFVHSKRSFT HDTTTDNIML RVFPDGHVLY
3D Structure
ModBase 3D Structure for P28476
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human GABRR2
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-GABRR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GABRR2 antibody
This is a rabbit polyclonal antibody against GABRR2. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR2 is a member of the rho subunit family and is a component of the GABA receptor complex.GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA receptor complex. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-30 BX490975.1 60-89 31-1586 BC130352.1 1-1556 1587-1631 M86868.1 1584-1628
Product Categories/Family for anti-GABRR2 antibody
Polyclonal; Ion Channel; Signal Proteins; Membrane Protein; Receptors;
Applications Tested/Suitable for anti-GABRR2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Immunohistochemistry (IHC) of anti-GABRR2 antibody
Rabbit Anti-GABRR2 Antibody
Formalin Fixed Paraffin Embedded Tissue: Human Adult heart
Observed Staining: Membrane(tight junctions - intercalated disks)
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy2/3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5-2.0 sec
Protocol located in Reviews and Data.

Western Blot (WB) of anti-GABRR2 antibody
Host: Rabbit
Target Name: GABRR2
Sample Type: 293T
Antibody Dilution: 1.0ug/mlGABRR2 is supported by BioGPS gene expression data to be expressed in HEK293T

Western Blot (WB) of anti-GABRR2 antibody
Host: Rabbit
Target Name: GABRR2
Sample Type: Human Fetal Brain
Antibody Dilution: 1.0ug/ml

Western Blot (WB) of anti-GABRR2 antibody
Host: Rabbit
Target Name: GABRR2
Sample Type: Human Fetal Liver
Antibody Dilution: 1.0ug/ml

Western Blot (WB) of anti-GABRR2 antibody
WB Suggested Anti-GABRR2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Hela cell lysate

NCBI/Uniprot data below describe general gene information for GABRR2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002034
[Other Products]
NCBI GenBank Nucleotide #
NM_002043
[Other Products]
UniProt Primary Accession #
P28476
[Other Products]
UniProt Related Accession #
P28476[Other Products]
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit rho-2
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor rho2 subunit
NCBI Official Symbol
GABRR2 [Similar Products]
NCBI Protein Information
gamma-aminobutyric acid receptor subunit rho-2
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit rho-2
UniProt Synonym Protein Names
GABA(A) receptor subunit rho-2; GABA(C) receptor
Protein Family
Gamma-aminobutyric acid receptor
UniProt Gene Name
GABRR2 [Similar Products]
UniProt Entry Name
GBRR2_HUMAN
NCBI Summary for GABRR2
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA type A receptor complex. This gene exists on chromosome 6q next to the gene encoding the rho 1 subunit of the GABA type A receptor, in a region thought to be associated with susceptibility for psychiatric disorders and epilepsy. Polymorphisms in this gene may also be associated with alcohol dependence, and general cognitive ability. [provided by RefSeq, Apr 2016]
Research Articles on GABRR2
1. GABAergic genes interacting with parenting in adolescent depressive symptoms: GABRR2 X perceived parental support interaction.
Precautions
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Disclaimer
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