Product Name
leucine rich repeat and Ig domain containing 1 (LINGO1), ELISA Kit
Full Product Name
Mouse Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, LINGO1 ELISA Kit
Product Synonym Names
Mouse Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (LINGO1) ELISA kit; FLJ14594; LERN1; LRRN6A; MGC17422; UNQ201; leucine rich repeat neuronal 6A; leucine-rich repeat neuronal 6A; leucine-rich repeat neuronal protein 1; leucine rich repeat and Ig domain containing 1
Product Gene Name
LINGO1 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q9D1T0
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of LINGO1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for LINGO1 purchase
MBS9316708 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the leucine rich repeat and Ig domain containing 1 (LINGO1) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LINGO1. The ELISA analytical biochemical technique of the MBS9316708 kit is based on LINGO1 antibody-LINGO1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LINGO1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LINGO1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for LINGO1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_851419.1
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NCBI GenBank Nucleotide #
NM_181074.4
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UniProt Primary Accession #
Q9D1T0
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UniProt Secondary Accession #
Q3TQJ4; Q6VVF9; Q7TT38[Other Products]
UniProt Related Accession #
Q9D1T0[Other Products]
Molecular Weight
69,101 Da
NCBI Official Full Name
leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
NCBI Official Synonym Full Names
leucine rich repeat and Ig domain containing 1
NCBI Official Symbol
Lingo1 [Similar Products]
NCBI Official Synonym Symbols
LERN1; Lrrn6a; UNQ201; LINGO-1; AV148400; 4930471K13Rik
[Similar Products]
NCBI Protein Information
leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine rich repeat neuronal 6A; leucine-rich repeat neuronal 6A; leucine-rich repeat neuronal protein 1; leucine-rich repeat neuronal protein 6A
UniProt Protein Name
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
UniProt Synonym Protein Names
Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
Protein Family
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein
UniProt Gene Name
Lingo1 [Similar Products]
UniProt Synonym Gene Names
Lern1; Lrrn6a [Similar Products]
UniProt Entry Name
LIGO1_MOUSE
UniProt Comments for LINGO1
LINGO1: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Cellular Component: membrane; integral to membrane; plasma membrane; intracellular
Molecular Function: protein binding; epidermal growth factor receptor binding
Biological Process: negative regulation of oligodendrocyte differentiation; protein kinase B signaling cascade; neurite development; central nervous system neuron development
Research Articles on LINGO1
1. LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.