Product Name
AQP1, Polyclonal Antibody
Popular Item
Full Product Name
AQP1 Antibody
Product Synonym Names
AQP 1; AQP CHIP; AQP-1; AQP1; AQP1_HUMAN; aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1 (Colton blood group); Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; Channel forming integral protein 28kDa; Channel like integral membrane protein 28 kDa; CHIP 28; CHIP28; CO; Colton blood group; Growth factor induced delayed early response protein; MGC26324; Urine water channel; Water channel protein CHIP 29; Water channel protein CHIP29; Water channel protein for red blood cells and kidney proximal tubule
Product Gene Name
anti-AQP1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P29972
Species Reactivity
Human, Mouse, Rat
Specificity
AQP1 antibody detects endogenous levels of total AQP1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide
Subcellular Location
Membrane.
Tissue Specificity
Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-AQP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AQP1 antibody
Function: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Subunit Structure: Homotetramer. Interacts with EPHB2; involved in endolymph production in the inner ear (By similarity). Identified in a complex with STOM.
Similarity: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). Belongs to the MIP/aquaporin (TC 1.A.8) family.
Applications Tested/Suitable for anti-AQP1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-AQP1 antibody
WB: 1:500-1:1000
Western Blot (WB) of anti-AQP1 antibody
Western blot analysis of extracts from HepG2, using AQP1 Antibody. Lane 1 was treated with the blocking peptide.
Western Blot (WB) of anti-AQP1 antibody
Western blot analysis of extracts from rat brain cells, using AQP1 antibody.
NCBI/Uniprot data below describe general gene information for AQP1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_932766.1
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NCBI GenBank Nucleotide #
NM_198098.3
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UniProt Primary Accession #
P29972
[Other Products]
UniProt Secondary Accession #
Q8TBI5; Q8TDC1; B5BU39; E7EM69; E9PC21; F5GY19[Other Products]
UniProt Related Accession #
P29972[Other Products]
Molecular Weight
Observed: 29 kD
Predicted: 29 kDa
NCBI Official Full Name
aquaporin-1 isoform 1
NCBI Official Synonym Full Names
aquaporin 1 (Colton blood group)
NCBI Official Symbol
AQP1 [Similar Products]
NCBI Official Synonym Symbols
CO; CHIP28; AQP-CHIP
[Similar Products]
NCBI Protein Information
aquaporin-1
UniProt Protein Name
Aquaporin-1
UniProt Synonym Protein Names
Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule
UniProt Gene Name
AQP1 [Similar Products]
UniProt Synonym Gene Names
CHIP28; AQP-1 [Similar Products]
NCBI Summary for AQP1
This gene encodes a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imbalance in ocular fluid movement. [provided by RefSeq, Aug 2016]
UniProt Comments for AQP1
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Research Articles on AQP1
1. Data show that miR-320 negatively regulates aquaporin 1 (AQP1) expression by targeting its 3' untranslated regions (3'-UTR).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
