Full Product Name
AGR3 Polyclonal Antibody
Product Synonym Names
AG3; HAG3; hAG-3; BCMP11; PDIA18
Product Gene Name
anti-AGR3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
0.6mg/mL (lot specific)
Immunogen
Recombinant protein of human AGR3
Calculated Molecular Weight: 19kDa
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-AGR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AGR3 antibody
Anterior gradient protein 3 homolog is a protein that in humans is encoded by the AGR3 gene. The deduced 166-amino acid protein has an N-terminal signal sequence. Fluorescence-tagged BCMP11 localized in secretory or endosome-like organelles in transfected breast carcinoma cell lines. Immunohistochemical analysis showed that expression of BCMP11 was restricted in normal tissues, with significant staining of only the epithelial lining of colonic mucosa. However, BCMP11 was detected in 43 of 58 (74%) breast cancer tissues tested, but not in normal breast ductal epithelial cells. In cancerous epithelial cells, BCMP11 localized to the cytoplasm.
Applications Tested/Suitable for anti-AGR3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-AGR3 antibody
WB: 1:200-1:1000
IHC: 1:15-1:50
Western Blot (WB) of anti-AGR3 antibody
Western Blot analysis of MCF7 cell and Human colon tissue using AGR3 Polyclonal Antibody at dilution of 1:150
Immunohistochemistry (IHC) of anti-AGR3 antibody
Immunohistochemistry of paraffin-embedded Human colon cancer using AGR3 Polyclonal Antibody at dilution of 1:15
Immunohistochemistry (IHC) of anti-AGR3 antibody
Immunohistochemistry of paraffin-embedded Human thyroid cancer using AGR3 Polyclonal Antibody at dilution of 1:15
NCBI/Uniprot data below describe general gene information for AGR3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_789783.1
[Other Products]
NCBI GenBank Nucleotide #
NM_176813.4
[Other Products]
UniProt Secondary Accession #
A4D120[Other Products]
UniProt Related Accession #
Q8TD06[Other Products]
Molecular Weight
19,171 Da
NCBI Official Full Name
anterior gradient protein 3 homolog
NCBI Official Synonym Full Names
anterior gradient 3
NCBI Official Symbol
AGR3 [Similar Products]
NCBI Official Synonym Symbols
AG3; AG-3; HAG3; hAG-3; BCMP11; PDIA18
[Similar Products]
NCBI Protein Information
anterior gradient protein 3 homolog; anterior gradient homolog 3; breast cancer membrane protein 11; protein disulfide isomerase family A, member 18
UniProt Protein Name
Anterior gradient protein 3 homolog
UniProt Synonym Protein Names
Breast cancer membrane protein 11
Protein Family
Anterior gradient protein
UniProt Gene Name
AGR3 [Similar Products]
UniProt Synonym Gene Names
BCMP11; AG-3; AG3; hAG-3 [Similar Products]
UniProt Entry Name
AGR3_HUMAN
UniProt Comments for AGR3
AGR3: Belongs to the AGR family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 7p21.1
Cellular Component: extracellular region
Molecular Function: protein binding
Research Articles on AGR3
1. AGR3 was is predominantly expressed in liver cholangiocytes but not present in liver hepatocytes, making this protain a good marker for differential diagnosis of intrahepatic cholangiocarcinoma
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
