EIF1AX, Polyclonal Antibody

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

Affinity Purified

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Small volumes of anti-EIF1AX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This is a rabbit polyclonal antibody against EIF1AX. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA.

Polyclonal; RNA Binding Proteins; Drugs and Drug Metabolism; DNA/RNA/Protein Interactions;

Western Blot (WB)

WB Suggested Anti-EIF1AX Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:2500
Positive Control: Human brain

16kDa

eukaryotic translation initiation factor 1A X-linked

eukaryotic translation initiation factor 1A, X-chromosomal

Eukaryotic translation initiation factor 1A, X-chromosomal

EIF1A; EIF4C; eIF-1A X isoform; eIF-4C  [Similar Products]

IF1AX_HUMAN

This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]

EIF1AX: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. Belongs to the eIF-1A family

Protein type: Translation initiation; Translation; RNA-binding

Chromosomal Location of Human Ortholog: Xp22.12

Cellular Component: cytosol

Molecular Function: protein binding; translation factor activity, nucleic acid binding; translation initiation factor activity

Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression

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