Product Name
TUBB2B, Blocking Peptide
Full Product Name
TUBB2B Peptide - N-terminal region
Product Gene Name
TUBB2B blocking peptide
[Similar Products]
Product Synonym Gene Name
DKFZp566F223; FLJ98847; MGC8685; TUBB-PARALOG; bA506K6.1[Similar Products]
TUBB2B peptide (MBS3241872) is used for blocking the activity of TUBB2B antibody (MBS3216973)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
GGGTGSGMGT LLISKIREEY PDRIMNTFSV MPSPKVSDTV VEPYNATLSV
3D Structure
ModBase 3D Structure for Q9BVA1
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of TUBB2B blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
TUBB2B blocking peptide
This is a synthetic peptide designed for use in combination with anti-TUBB2B Antibody, made
Target Description: The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria.
Product Categories/Family for TUBB2B blocking peptide
Peptide
Applications Tested/Suitable for TUBB2B blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for TUBB2B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_821080
[Other Products]
NCBI GenBank Nucleotide #
NM_178012
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UniProt Primary Accession #
Q9BVA1
[Other Products]
UniProt Related Accession #
Q9BVA1[Other Products]
NCBI Official Full Name
tubulin beta-2B chain
NCBI Official Synonym Full Names
tubulin beta 2B class IIb
NCBI Official Symbol
TUBB2B [Similar Products]
NCBI Official Synonym Symbols
CDCBM7; PMGYSA; bA506K6.1
[Similar Products]
NCBI Protein Information
tubulin beta-2B chain
UniProt Protein Name
Tubulin beta-2B chain
UniProt Gene Name
TUBB2B [Similar Products]
NCBI Summary for TUBB2B
The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010]
UniProt Comments for TUBB2B
Tubulin is the major constituent of microtubules (PubMed:23001566, PubMed:28013290, PubMed:26732629). It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (). Plays a critical role in proper axon guidance in both central and peripheral axon tracts (PubMed:23001566). Implicated in neuronal migration (PubMed:19465910).
Research Articles on TUBB2B
1. CPAP regulates delivery of its bound beta-tubulin to define the size of microtubule-based cellular structures using a "clutch-like" mechanism.
Precautions
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Disclaimer
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