Biotin - anti human CD63 - Clone TEA3/18
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产品名称: Biotin - anti human CD63 - Clone TEA3/18
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Biotin - anti human CD63 - Clone TEA3/18
Biotin - anti human CD63 - Clone TEA3/18
的详细介绍
Biotin
- anti Human
CD63 - TEA3/18
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TEA3/18
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IgG1
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FCM
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Biotin
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Please refer to the Certificate of Analysis for the lot-specific concentration.
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Tissue / cell preparation (Human cytochrome B enriched cells).
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Human
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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RUO
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CD63, clone TEA3/18, is a mAb intended for the identification of activated platelets. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
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This antibody reacts with the CD63- antigen, which is expressed in platelet lysosomes that is translocated to the platelet surface upon activation with strong agonists. The antigen is also present in most peripheral blood cells (not in erythrocytes) and in many tissues; both surface and cytoplasmatic locations are reported. It has been reported a cellular expression of CD63 in intracellular lysosomal, endosomal and granulate protein, in Weibel Palade bodies of vascular endothelium, in degranulated neutrophils, monocytes, macrophages and endothelium.
It has been showed an Immunohistochemistry staining of fibroblasts, osteoclasts, smooth muscle, neural tissue (brain white matter and peripheral nerves) and synovial lining cells
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LIMP, MLA1, PTLGP40, gp55, granulophysin, LAMP-3, ME491, NGA, Lysosomal-associated membrane protein 3, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, Tetraspanin-30, Tspan-35
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53 kDa
