Catalogue number
ANT-122
Type
Mouse Anti Human Monoclonal.
Introduction
IFN-alpha is produced by macrophages, IFN-alpha has antiviral activities and stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Clone
NYRhIFN-A (neut).
Immunogen
r.Human IFN Alpha.
Ig Subclass
Mouse IgG1.
Purification Method
Ion exchange.
Formulation
1mg/ml in PBS (after reconstitution).
Shipping Conditions
Antibody is shipped lyophilized at ambient temperature.
Storage Procedures
In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.
Solubility
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Applications
Direct ELISA (Does not work in Western Blotting). This is a Neutralizing antibody.
Titer
By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).
Note
The antibody can be used for Capture ELISA together with ProSpec’s Mouse Anti Human IFN-alpha Western Blot antibody.
References
Title:Multidirectional interactions are bridging human NK cells with plasmacytoid and monocyte-derived dendritic cells during innate immune responses.
Publication:Published online before print July 27, 2006, doi: 10.1182/blood-2006-02-004028 Blood December 1, 2006 vol. 108 no. 12 3851-3858.
Link:http://bloodjournal.hematologylibrary.org/content/108/12/3851.full
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
