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Factor D

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产品名称: Factor D
产品型号: A409
产品展商: Quidel Corporation
产品文档: 无相关文档

简单介绍

Purified human complement Factor D. Factor D is unique to the Alternative Complement Pathway. It consists of a single peptide chain with a molecular weight of 24 kD. Factor D is a specific serine protease which cleaves Factor B complexed with C3b (or hydrolyzed C3) in a single position to yield Bb and Ba.


Factor D  的详细介绍

Factor D

For Research Use Only. Not for use in diagnostic procedures.

Purified human complement Factor D. Factor D is unique to the Alternative Complement Pathway. It consists of a single peptide chain with a molecular weight of 24 kD. Factor D is a specific serine protease which cleaves Factor B complexed with C3b (or hydrolyzed C3) in a single position to yield Bb and Ba.

All Quidel complement components are tested for functional activity in a standard lytic or applicable functional assay and for biochemical purity by SDS- polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer.

Quidel's purified human complement components are useful in a wide variety of immunochemical and research applications. 

References

Marks, R. Hindmarsh, E. Complement activation occurs on subendothelial extracelluslar matrix in vitro and is initiated by retraction or removal of overlying endothelial cells, J Immunol 160:6128-6136, 1998.

Barbashov, S., Wang C., Nicholson-Weller, A. Serum amyloid P component forms a stable complex with human C5b-6, J. Immunol. 158:3830-3835, 1997.

Product Specifications

Concentration

0.1 mg/mL

Volume/vial

250 µL/vial

Storage

At or below –70°C

Purity

> 90%

Buffer

PBS

Ordering Information

Catalog Number Kit Size / Case Size
A409
250 µL/vial
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