μ-conotoxin-PIIIA
Blocker of Nav1.4 channels
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产品名称: μ-conotoxin-PIIIA
Blocker of Nav1.4 channels
产品型号: 08CON006-00100
产品展商: 其他品牌
产品文档: 无相关文档
简单介绍
μ-conotoxin-PIIIA
Blocker of Nav1.4 channels
的详细介绍
μ-conotoxin-PIIIA
Blocker of Nav1.4 channels
μ-Conotoxin PIIIA (mu-conotoxin PIIIA) is a conotoxin that has been isolated from the venom of the cone Conus purpurascens. μ-conotoxin PIIIA demonstrates a higher affinity for the mammalian muscle sodium channel Nav1.4 (IC50 ~ 44 nM) than for the CNS Nav1.2 subtype (IC50 ~ 640 nm). μ-Conotoxin PIIIA blocks more irreversibly amphibian muscle sodium channels than mammalian ones.
