SNX482
Selective blocker of Cav2.3 channel
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产品名称: SNX482
Selective blocker of Cav2.3 channel
产品型号: 08SNX001-00050
产品展商: 其他品牌
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简单介绍
SNX482
Selective blocker of Cav2.3 channel
的详细介绍
SNX482
Selective blocker of Cav2.3 channel
SNX-482 has been isolated from the venom of the Spider Hysterocrates gigas (African tarantula). SNX-482 modulates the R-type current associated with the class α1E calcium channel (Cav2.3 from the CACNA1E gene). SNX-482 antagonizes channel activation by inducing a depolarizing shift in the activation potential, thus preventing the channel from undergoing normal membrane depolarization. SNX-482 acts rapidly and maintains its effect.