alpha-cobratoxin
α7 nicotinic acetylcholine receptor (nAChR) antagonist
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产品名称: alpha-cobratoxin
α7 nicotinic acetylcholine receptor (nAChR) antagonist
产品型号: CBT001
产品展商: 其他品牌
产品文档: 无相关文档
简单介绍
alpha-cobratoxin
α7 nicotinic acetylcholine receptor (nAChR) antagonist
的详细介绍
alpha-cobratoxin
α7 nicotinic acetylcholine receptor (nAChR) antagonist
α-cobratoxin (alpha-elapitoxin-Nk2a) has been isolated from the venom of the Naja kaouthia cobra snake. α-cobratoxin preferentially blocks muscular and neuronal α 7/CHRNA7 nicotinic acetylcholine receptor (Kd = 55 pM). α-cobratoxin is involved in paralysis by preventing acetylcholine binding to the nAChR. This toxin has shown to cause reduction of tumor growth in mice lung cancer.
