Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
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产品名称: Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
产品型号: 12IBX001-50010
产品展商: 其他品牌
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简单介绍
Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
的详细介绍
Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulus scorpion venom. Iberiotoxin inhibits selectively the high conductance Ca2+-activated K+ channel (KCa1.1) at nanomolar concentrations (IC50 ~2 nM). This toxin does not affect other types of calcium-dependent or voltage-dependent K+ channels. Iberiotoxin is a valuable tool to study specifically Maxi-K channels.
