Leiurotoxin-1 Dab7
SK2 channel blocker
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产品名称: Leiurotoxin-1 Dab7
SK2 channel blocker
产品型号: LED01-00100
产品展商: 其他品牌
产品文档: 无相关文档
简单介绍
Leiurotoxin-1 Dab7
SK2 channel blocker
的详细介绍
Leiurotoxin-1 Dab7
SK2 channel blocker
Leiuorotoxin-Dab7 (Lei-Dab7) is a mutated version of Leiurotoxin, a peptide identified from the venom of the scorpion Leiurus quinquestriatus hebraeus. The Dab amino acid in position 7 confers to this compound a high selectivity for SK2 channels among other channels. Lei-Dab7 exhibits > 200 fold selectivity for SK2 over SK1, SK3, IK, Kv and Kir channels. The IC50 for SK2 is about 3 nM.
